Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2292282 | 0.78 | FFAR4 (0.65) | MAOBFFAR1FFAR4 | |
| SCHEMBL15330178 | 0.78 | LIPG (0.47) | MAOBFFAR1FFAR4HRH3 | |
| SCHEMBL2292126 | 0.78 | MAOB (0.44) | MAOBFFAR1FFAR4SENP8SENP7 | |
| SCHEMBL2558687 | 0.77 | ENPP2 (0.60) | MAOBFFAR1FFAR4AKR1B1 | |
| SCHEMBL10784840 | 0.75 | LTA4H (0.64) | MAOBFFAR1FFAR4BCHEHRH3 | |
| SCHEMBL8593444 | 0.75 | FFAR1 (0.47) | MAOBFFAR1FFAR4SENP8SENP7 | |
| SCHEMBL9946094 | 0.74 | LPL (0.47) | MAOBFFAR1SENP8SENP7SENP6 | |
| SCHEMBL16440937 | 0.74 | APP (0.56) | MAOBFFAR1SENP8SENP7SENP6 | |
| SCHEMBL15196499 | 0.73 | FFAR1 (0.61) | MAOBFFAR1FFAR4BCHE | |
| SCHEMBL3760159 | 0.73 | ALDH1A1 (0.54) | MAOBBCHEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | MAOB 780/4885FFAR1 1083/4885FFAR4 1371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.