Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899791 | 0.88 | KMT2A (0.44) | RAB9ALMNANPC1ALDH1A1MEN1 | |
| SCHEMBL18678829 | 0.85 | NPC1 (0.45) | RAB9ALMNANPC1ALDH1A1MEN1 | |
| SCHEMBL8900778 | 0.84 | KMT2A (0.55) | RAB9ALMNANPC1ALDH1A1MEN1 | |
| SCHEMBL8898870 | 0.84 | MLYCD (0.45) | RAB9ANPC1ALDH1A1TMEM97SIGMAR1 | |
| SCHEMBL10050641 | 0.83 | RAB9A (0.40) | RAB9ALMNANPC1ALDH1A1TMEM97 | |
| Benzene SCHEMBL28672020 | 0.80 | RIPK1 (0.43) | RAB9ALMNANPC1MEN1KMT2A | |
| SCHEMBL4650526 | 0.80 | RIPK1 (0.43) | RAB9ALMNANPC1MEN1KMT2A | |
| SCHEMBL8897587 | 0.80 | ACHE (0.57) | RAB9ANPC1ALDH1A1SIGMAR1MEN1 | |
| SCHEMBL19601362 | 0.79 | NPY5R (0.45) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL8899758 | 0.78 | PPARG (0.48) | RAB9ANPC1TMEM97SIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8899745-B2 | Ophthalmic lenses modified with functional groups and methods of making thereof | NOVARTIS AG (CH) | 2014-12-02 | — | — | US | disclosed |
| US-20120147323-A1 | OPHTHALMIC LENSES MODIFIED WITH FUNCTIONAL GROUPS AND METHODS OF MAKING THEREOF | ALCON INC. (CH) | 2012-06-14 | — | — | US | disclosed |