Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358846 | 0.89 | NPC1 (0.47) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL93485 | 0.89 | NPC1 (0.47) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL14907494 | 0.87 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL4445599 | 0.87 | NPC1 (0.40) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL4446963 | 0.86 | APP (0.39) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL12269844 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL14540375 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL31085365 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL8823408 | 0.85 | LMNA (0.43) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL31085351 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379512-B1 | TRI-FUNCTIONAL UV-ABSORBING COMPOUNDS AND USE THEREOF | NOVARTIS AG (CH) | 2017-03-29 | — | — | EP | disclosed |
| US-8899745-B2 | Ophthalmic lenses modified with functional groups and methods of making thereof | NOVARTIS AG (CH) | 2014-12-02 | — | — | US | disclosed |
| US-8324256-B2 | Tri-functional UV-absorbing compounds and use thereof | NOVARTIS AG (CH) | 2012-12-04 | — | — | US | disclosed |
| US-20120147323-A1 | OPHTHALMIC LENSES MODIFIED WITH FUNCTIONAL GROUPS AND METHODS OF MAKING THEREOF | ALCON INC. (CH) | 2012-06-14 | — | — | US | disclosed |
| US-20100168359-A1 | TRI-FUNCTIONAL UV-ABSORBING COMPOUNDS AND USE THEREOF | ALCON INC. (CH) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168359-A1 | TRI-FUNCTIONAL UV-ABSORBING COMPOUNDS AND USE THEREOF | UACA, TCOF1, TTPA | ALDH1A1 992/4885MAPT 110/4885KDM4E 2399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.