SCHEMBL99475

SCHEMBL99475

CCOc1cc(N)c(Cl)cc1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
HSD17B10 Q99714 2/20 0.53
GAA P10253 1/20 0.50
DRD2 P14416 2/20 0.49
HTR4 Q13639 3/20 0.48
ACHE P22303 1/20 0.48
CYP3A4 P08684 2/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2D6 P10635 2/20 0.45
HTR3A P46098 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
CYP2C9 P11712 1/20 0.45
LMNA P02545 2/20 0.44
HTT P42858 2/20 0.44
HTR3E A5X5Y0 1/20 0.44
SLC22A1 O15245 1/20 0.44
HTR3B O95264 1/20 0.44
ALDH1A1 P00352 1/20 0.44
MPO P05164 1/20 0.44
ADRA2A P08913 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22987088 0.88 GAA (0.48) TSHRGAADRD2HTR4CYP3A4
SCHEMBL1804452 0.87 LMNA (0.51) TSHRHSD17B10GAADRD2HTR4
SCHEMBL11167484 0.87 HSD17B10 (0.49) TSHRHSD17B10GAADRD2HTR4
SCHEMBL29242370 0.87 GAA (0.50) TSHRHSD17B10GAADRD2HTR4
SCHEMBL11232189 0.86 TSHR (0.59) TSHRHSD17B10GAACYP3A4SMN1; SMN2
SCHEMBL11777279 0.85 TSHR (0.62) TSHRHSD17B10GAACYP3A4SMN1; SMN2
SCHEMBL9458494 0.84 ALDH1A1 (0.45) TSHRHSD17B10GAADRD2HTR4
SCHEMBL7373656 0.84 GAA (0.72) TSHRGAADRD2HTR4ACHE
SCHEMBL26238952 0.84 HTR4 (0.55) TSHRHSD17B10GAADRD2HTR4
SCHEMBL7367657 0.84 PTPN11 (0.52) TSHRHTR4CYP3A4LMNAADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119224147-A Detection method for mosapride citrate intermediate impurities 吉林修正药业新药开发有限公司 2024-12-31 CN claimed
CN-117986199-A Synthesis method of mosapride citrate impurity 珠海润都制药股份有限公司 2024-05-07 CN claimed
CN-115710232-A Compound containing triazolinone structure, preparation method thereof and application of compound as herbicide 中国农业大学 2023-02-24 CN claimed
CN-104961646-B Mosapride active metabolites, preparation method and uses thereof 沈阳药科大学 2017-02-22 CN claimed
JP-6306075-A None JP disclosed
CN-119241463-A Mosapride citrate impurity compound and preparation method thereof 吉林修正药业新药开发有限公司 2025-01-03 CN disclosed
CN-119246710-A Method for detecting fluorine impurities in mosapride citrate intermediate 吉林修正药业新药开发有限公司 2025-01-03 CN disclosed
CN-119246725-A Method for detecting fluorine impurities in mosapride citrate intermediate 吉林修正药业新药开发有限公司 2025-01-03 CN disclosed
CN-119224147-A Detection method for mosapride citrate intermediate impurities 吉林修正药业新药开发有限公司 2024-12-31 CN disclosed
CN-119224147-A Detection method for mosapride citrate intermediate impurities 吉林修正药业新药开发有限公司 2024-12-31 CN disclosed
CN-117986199-A Synthesis method of mosapride citrate impurity 珠海润都制药股份有限公司 2024-05-07 CN disclosed
CN-117986199-A Synthesis method of mosapride citrate impurity 珠海润都制药股份有限公司 2024-05-07 CN disclosed
EP-0815080-A1 DI-SUBSTITUTED 1,4-PIPERIDINE ESTERS AND AMIDES HAVING 5-HT 4? ANTAGONISTIC ACTIVITY BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) 1998-01-07 EP disclosed
JP-H06306075-A ETHOXYBENZAMIDE DERIVATIVE SANWA KAGAKU KENKYUSHO CO LTD 1994-11-01 JP disclosed
EP-0243959-B1 SUBSTITUTED BENZAMIDE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME Dainippon Pharmaceutical Co., Ltd. (JP) 1992-08-19 EP disclosed
EP-0213775-B1 NEW BENZAMIDES WALTON S.A. (ES) 1990-01-03 EP disclosed
US-4870074-A Substituted benzamide derivatives, for enhancing gastrointestinal motility DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1989-09-26 US disclosed
US-4772618-A NONAROMATIC CYCLIC (THIO)ETHER GROUPS, AMINE INTERMEDIATES, GASTROINTESTINAL DISORDERS FORDONAL, S.A. (ES) 1988-09-20 US disclosed
EP-0243959-A1 Substituted benzamide derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same Dainippon Pharmaceutical Co., Ltd. (JP) 1987-11-04 EP disclosed
EP-0213775-A1 New Benzamides WALTON S.A. (ES) 1987-03-11 EP disclosed