Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.62 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.62 |
| ▸ | PNP | P00491 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8829787 | 0.78 | PNP (0.49) | HRH3HRH4PNPTSHRKDM4E | |
| SCHEMBL28239625 | 0.77 | HRH3 (0.58) | HRH3HRH4PNPDAOMEN1 | |
| SCHEMBL10751303 | 0.72 | AR (0.40) | HRH3HRH4KDM4EL3MBTL1 | |
| SCHEMBL28343693 | 0.71 | L3MBTL1 (0.53) | HRH3HRH4TSHRMAPTL3MBTL1 | |
| SCHEMBL10734739 | 0.71 | LMNA (0.48) | HRH3HRH4PNPTSHRKDM4E | |
| SCHEMBL4649823 | 0.70 | KDM4E (0.45) | HRH3HRH4PNPTSHRKDM4E | |
| SCHEMBL7011364 | 0.70 | PNP (0.54) | HRH3HRH4PNPTSHRKDM4E | |
| SCHEMBL41191 | 0.69 | L3MBTL1 (0.59) | HRH3HRH4TSHRMAPTL3MBTL1 | |
| SCHEMBL29830938 | 0.69 | L3MBTL1 (0.59) | HRH3HRH4TSHRMAPTL3MBTL1 | |
| SCHEMBL16598063 | 0.69 | HRH3 (0.53) | HRH3HRH4MAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315493-B2 | Phenylpyridine derivative and drug containing same | KOWA COMPANY, LTD. (JP) | 2016-04-19 | — | — | US | disclosed |
| EP-2687523-B1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND DRUG CONTAINING SAME | KOWA CO (JP) | 2016-01-06 | — | — | EP | disclosed |
| EP-2484675-B1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME | KOWA CO (JP) | 2014-11-05 | — | — | EP | disclosed |
| US-8778954-B2 | Phenylpyridine derivative and medicinal agent comprising same | KOWA COMPANY, LTD. (JP) | 2014-07-15 | — | — | US | disclosed |
| EP-2687523-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND DRUG CONTAINING SAME | Kowa Company Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |
| US-20140011823-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND DRUG CONTAINING SAME | KOWA COMPANY, LTD. (JP) | 2014-01-09 | — | — | US | disclosed |
| EP-2484675-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME | Kowa Company, Ltd. (JP) | 2012-08-08 | — | — | EP | disclosed |
| US-20120165353-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME | KOWA COMPANY, LTD. (JP) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011823-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND DRUG CONTAINING SAME | AGTR2, AGTR1, PPARD | HRH3 732/4885HRH4 256/4885PNP 3169/4885 |
| US-20120165353-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME | AGTR2, AGTR1, PPARD | HRH3 543/4885HRH4 222/4885PNP 3298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.