SCHEMBL9949648

SCHEMBL9949648

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nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19668114 1.00 USP2 (0.35) USP2NPSR1TDP1
SCHEMBL22495179 1.00 USP2 (0.35) USP2NPSR1TDP1
SCHEMBL30744046 1.00 USP2 (0.35) USP2NPSR1TDP1
SCHEMBL30043738 0.81 USP2 (0.34) USP2NPSR1TDP1
SCHEMBL31735732 0.81 USP2 (0.34) USP2NPSR1TDP1
SCHEMBL31618595 0.81 USP2 (0.34) USP2NPSR1TDP1
SCHEMBL3992801 0.80 USP2 (0.37) USP2NPSR1TDP1
SCHEMBL13206360 0.75 USP2 (0.40) USP2NPSR1TDP1
SCHEMBL1244992 0.75 USP2 (0.40) USP2NPSR1TDP1
SCHEMBL3625807 0.75 USP2 (0.38) USP2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404479-B2 Laundry detergent composition containing graft copolymer and benefit agent THE PROCTER & GAMBLE COMPANY (US) 2025-09-02 US claimed
US-12234253-B2 Silicone compounds with a substituted amine group and a benefit agent moiety THE PROCTER & GAMBLE COMPANY (US) 2025-02-25 US claimed
US-20250051370-A1 SILICONE COMPOUNDS PROCTER & GAMBLE (US) 2025-02-13 US claimed
US-20240010954-A1 LAUNDRY DETERGENT COMPOSITION CONTAINING GRAFT COPOLYMER AND BENEFIT AGENT THE PROCTER & GAMBLE COMPANY 2024-01-11 US claimed
US-20220064191-A1 SILICONE COMPOUNDS PROCTER & GAMBLE (US) 2022-03-03 US claimed
EP-3218425-B1 SILICONE COMPOUNDS PROCTER & GAMBLE (US) 2020-05-13 EP claimed
CN-111138665-A Organosilicon compounds 宝洁公司 2020-05-12 CN claimed
US-20170327647-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2017-11-16 US claimed
US-20160137674-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2016-05-19 US claimed
US-12404479-B2 Laundry detergent composition containing graft copolymer and benefit agent THE PROCTER & GAMBLE COMPANY (US) 2025-09-02 US disclosed
US-12234253-B2 Silicone compounds with a substituted amine group and a benefit agent moiety THE PROCTER & GAMBLE COMPANY (US) 2025-02-25 US disclosed
US-20250051370-A1 SILICONE COMPOUNDS PROCTER & GAMBLE (US) 2025-02-13 US disclosed
US-20240018446-A1 LAUNDRY DETERGENT COMPOSITION CONTAINING TWO GRAFT COPOLYMER THE PROCTER & GAMBLE COMPANY 2024-01-18 US disclosed
EP-4306628-A1 LAUNDRY DETERGENT COMPOSITION CONTAINING TWO GRAFT COPOLYMER The Procter & Gamble Company (US) 2024-01-17 EP disclosed
US-20200095267-A1 SILICONE COMPOUNDS PROCTER & GAMBLE (US) 2020-03-26 US disclosed
US-10590148-B2 Silicone compounds comprising a ketone or aldehyde benefit agent moiety THE PROCTER & GAMBLE COMPANY (US) 2020-03-17 US disclosed
EP-3572449-A1 SILICONE COMPOUNDS The Procter & Gamble Company (US) 2019-11-27 EP disclosed
US-20170327647-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2017-11-16 US disclosed
US-20160137674-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2016-05-19 US disclosed
US-20120165552-A1 7,10,13-CYCLOHEXADECATRIEN-16-OLIDE, AND FLAVOR OR FRAGRANCE COMPOSITION, FRAGRANCE OR COSMETIC PRODUCT, FOOD PRODUCT OR BEVERAGE OR TOILETRY PRODUCT COMPRISING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160137674-A1 SILICONE COMPOUNDS SMCHD1, SRI, SMS USP2 2636/4885NPSR1 2458/4885TDP1 2993/4885
US-20200095267-A1 SILICONE COMPOUNDS SMCHD1, SRI, SMS USP2 2636/4885NPSR1 2458/4885TDP1 2993/4885
US-20120165552-A1 7,10,13-CYCLOHEXADECATRIEN-16-OLIDE, AND FLAVOR OR FRAGRANCE COMPOSITION, FRAGRANCE OR COSMETIC PRODUCT, FOOD PRODUCT OR BEVERAGE OR TOILETRY PRODUCT COMPRISING THE SAME OR10J3, TAS2R40, CUTA USP2 3914/4885NPSR1 1471/4885TDP1 4774/4885
US-20250051370-A1 SILICONE COMPOUNDS SMCHD1, SRI, SMS USP2 2636/4885NPSR1 2458/4885TDP1 2993/4885
US-10590148-B2 Silicone compounds comprising a ketone or aldehyde benefit agent moiety SMN1; SMN2, KARS1, ACADM USP2 2453/4885NPSR1 3416/4885TDP1 3304/4885
US-12234253-B2 Silicone compounds with a substituted amine group and a benefit agent moiety SMS, SRM, AAAS USP2 2777/4885NPSR1 611/4885TDP1 1530/4885
US-20220064191-A1 SILICONE COMPOUNDS SMCHD1, SRI, SMS USP2 2636/4885NPSR1 2458/4885TDP1 2993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.