Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5985505 | 0.97 | ALDH1A1 (0.37) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL5984550 | 0.97 | ALDH1A1 (0.37) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL5985193 | 0.97 | ALDH1A1 (0.37) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL5985442 | 0.97 | ALDH1A1 (0.37) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL5985095 | 0.97 | ALDH1A1 (0.37) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL5985061 | 0.97 | ALDH1A1 (0.37) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL5984155 | 0.97 | ALDH1A1 (0.37) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL5986083 | 0.97 | ALDH1A1 (0.37) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL5985888 | 0.97 | ALDH1A1 (0.37) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL5983723 | 0.97 | ALDH1A1 (0.37) | ALDH1A1TDP1CYP3A4TSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230099694-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-03-30 | — | — | US | disclosed |
| US-20210052575-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-02-25 | — | — | US | disclosed |
| US-20200061056-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-02-27 | — | — | US | disclosed |
| US-20190167672-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-06-06 | — | — | US | disclosed |
| US-20180318294-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2018-11-08 | — | — | US | disclosed |
| US-20180092907-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2018-04-05 | — | — | US | disclosed |
| EP-2151233-B1 | TWO-COMPONENT OXIDATIVE HAIR DYE COMPOSITION | KAO CORP (JP) | 2017-08-09 | — | — | EP | disclosed |
| EP-2151232-B1 | OXIDATIVE HAIR DYE COMPOSITION | KAO CORP (JP) | 2017-04-12 | — | — | EP | disclosed |
| US-20170071933-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-03-16 | — | — | US | disclosed |
| EP-2753617-B9 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMA CO LTD (JP) | 2017-01-25 | — | — | EP | disclosed |
| US-20040156815-A1 | Hair cleansing composition | KAO CORPORATION (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1433464-A2 | Hair cleansing composition | Kao Corporation (JP) | 2004-06-30 | — | — | EP | disclosed |
| EP-1433465-A2 | Hair cosmetic composition | Kao Corporation (JP) | 2004-06-30 | — | — | EP | disclosed |
| EP-1433466-A2 | Hair cleansing composition | Kao Corporation (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-20040115162-A1 | Dermatological preparations | KAO CORPORATION (JP) | 2004-06-17 | — | — | US | disclosed |
| US-6685953-B1 | WATER RETENTION CAPACITY; MOISTURIZER; ALKOXYALKYAMIDES OF ALKYLENEDICARBOXYLIC ACIDS | KAO CORPORATION (JP) | 2004-02-03 | — | — | US | disclosed |
| US-20030158164-A1 | Novel antiandrogenic agent | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-08-21 | — | — | US | disclosed |
| EP-1304334-A1 | NOVEL ANTIANDROGENIC AGENT | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-1219631-A1 | ANTIANDROGEN AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-1166766-A1 | EXTERNAL PREPARATION COMPOSITIONS | Kao Corporation (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230099694-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | ALDH1A1 1257/4885TDP1 4048/4885CYP3A4 222/4885 |
| US-20170071933-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | ALDH1A1 1257/4885TDP1 4048/4885CYP3A4 222/4885 |
| US-20180318294-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | ALDH1A1 1257/4885TDP1 4048/4885CYP3A4 222/4885 |
| US-20210052575-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, SULT2A1, CYP4Z1 | ALDH1A1 1445/4885TDP1 4353/4885CYP3A4 121/4885 |
| US-20200061056-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | ALDH1A1 1257/4885TDP1 4048/4885CYP3A4 222/4885 |
| US-20180092907-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | ALDH1A1 1257/4885TDP1 4048/4885CYP3A4 222/4885 |
| US-20190167672-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | ALDH1A1 1257/4885TDP1 4048/4885CYP3A4 222/4885 |
| US-20030158164-A1 | Novel antiandrogenic agent | NR5A1, CYP19A1, HSD17B11 | ALDH1A1 399/4885TDP1 3394/4885CYP3A4 728/4885 |
| US-20040156815-A1 | Hair cleansing composition | CUTA, TRPA1, SHH | ALDH1A1 2683/4885TDP1 3242/4885CYP3A4 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.