Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145175 | 0.86 | ERN1 (0.47) | ERN1CYP2A6PPARAPTPN1PRKDC | |
| SCHEMBL13437720 | 0.79 | ERN1 (0.47) | ERN1CYP2A6PTPN1PRKDCPTGDR2 | |
| SCHEMBL15310930 | 0.79 | ALDH1A1 (0.35) | ERN1ALDH1A1TYRMEN1KMT2A | |
| SCHEMBL27993122 | 0.75 | ERN1 (0.43) | ERN1CYP2A6PTPN1PRKDCPTGDR2 | |
| SCHEMBL15310956 | 0.75 | MEN1 (0.42) | ERN1PTPN1ALDH1A1LMNAMEN1 | |
| SCHEMBL3689758 | 0.73 | LMNA (0.48) | ERN1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL20607737 | 0.71 | PRKDC (0.42) | ERN1PPARAPRKDCALDH1A1TYR | |
| SCHEMBL25216063 | 0.71 | ALDH1A1 (0.49) | ERN1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL29513843 | 0.70 | PRKDC (0.53) | ERN1PTPN1PRKDCALDH1A1LMNA | |
| SCHEMBL28860021 | 0.70 | PRKDC (0.57) | ERN1PRKDCALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655303-B1 | HYDROGENATION OF ESTERS OR CARBONYL GROUPS WITH TETRADENTATE AMINO/IMINO-THIOETHER BASED RUTHENIUM COMPLEXES | FIRMENICH & CIE (CH) | 2017-02-22 | — | — | EP | disclosed |
| US-8614345-B2 | Hydrogenation of esters or carbonyl groups with tetradentate amino/imino-thioether based ruthenium complexes | FIRMENICH SA (CH) | 2013-12-24 | — | — | US | disclosed |
| EP-2655303-A1 | HYDROGENATION OF ESTERS OR CARBONYL GROUPS WITH TETRADENTATE AMINO/IMINO-THIOETHER BASED RUTHENIUM COMPLEXES | Firmenich SA (CH) | 2013-10-30 | — | — | EP | disclosed |
| US-20130274487-A1 | HYDROGENATION OF ESTERS OR CARBONYL GROUPS WITH TETRADENTATE AMINO/IMINO-THIOETHER BASED RUTHENIUM COMPLEXES | FIRMENICH SA (CH) | 2013-10-17 | — | — | US | disclosed |
| WO-2012084810-A1 | HYDROGENATION OF ESTERS OR CARBONYL GROUPS WITH TETRADENTATE AMINO/IMINO-THIOETHER BASED RUTHENIUM COMPLEXES | FIRMENICH SA (CH) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274487-A1 | HYDROGENATION OF ESTERS OR CARBONYL GROUPS WITH TETRADENTATE AMINO/IMINO-THIOETHER BASED RUTHENIUM COMPLEXES | ADH5, ADH1A, ADH1C | ERN1 539/4885CYP2A6 2078/4885PPARA 852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.