Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14269535 | 0.74 | RAB9A (0.50) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL374022 | 0.70 | RAB9A (0.74) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL29631691 | 0.70 | RAB9A (0.74) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL2967468 | 0.65 | RAB9A (0.40) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL14889313 | 0.65 | RAB9A (0.55) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL19753898 | 0.65 | RAB9A (0.50) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL5053299 | 0.65 | NPC1 (0.87) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL5051826 | 0.65 | KDR (0.68) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| 2-Phenyl-1H-Indole SCHEMBL29363616 | 0.63 | NPC1 (1.00) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| Methane SCHEMBL28704887 | 0.63 | KDR (0.66) | RAB9ANPC1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111100056-B | Synthetic method for preparing 3-thiophenyl indole compound by oxygen oxidation without transition metal catalysis | 浙江工业大学 | 2021-07-06 | — | — | CN | claimed |
| CN-111100056-A | Synthetic method for preparing 3-thiophenyl indole compound by oxygen oxidation without transition metal catalysis | 浙江工业大学 | 2020-05-05 | — | — | CN | claimed |
| CN-111100056-B | Synthetic method for preparing 3-thiophenyl indole compound by oxygen oxidation without transition metal catalysis | 浙江工业大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-111100056-B | Synthetic method for preparing 3-thiophenyl indole compound by oxygen oxidation without transition metal catalysis | 浙江工业大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-111100056-B | Synthetic method for preparing 3-thiophenyl indole compound by oxygen oxidation without transition metal catalysis | 浙江工业大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-111100056-A | Synthetic method for preparing 3-thiophenyl indole compound by oxygen oxidation without transition metal catalysis | 浙江工业大学 | 2020-05-05 | — | — | CN | disclosed |
| CN-111100056-A | Synthetic method for preparing 3-thiophenyl indole compound by oxygen oxidation without transition metal catalysis | 浙江工业大学 | 2020-05-05 | — | — | CN | disclosed |
| CN-111100056-A | Synthetic method for preparing 3-thiophenyl indole compound by oxygen oxidation without transition metal catalysis | 浙江工业大学 | 2020-05-05 | — | — | CN | disclosed |
| US-9657012-B2 | FAAH inhibitors | IRONWOOD PHARMACEUTICALS, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| EP-2655356-B1 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS INC (US) | 2016-08-03 | — | — | EP | disclosed |
| CN-103502237-B | Faah inhibitor | IRONWOOD PHARMACEUTICALS, INC. (US) | 2016-01-20 | — | — | CN | disclosed |
| US-20150175599-A1 | FAAH Inhibitors | IRONWOOD PHARMACEUTICALS, INC. (US) | 2015-06-25 | — | — | US | disclosed |
| CN-103502237-A | FAAH inhibitors | IRONWOOD PHARMACEUTICALS INC | 2014-01-08 | — | — | CN | disclosed |
| EP-2655356-A1 | FAAH INHIBITORS | Ironwood Pharmaceuticals, Inc. (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012088431-A1 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012088469-A1 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2012-06-28 | — | — | WO | disclosed |
| CN-1261412-C | Indole derivatives as COXII inhibitors | HOFFMANN LA ROCHE (CH) | 2006-06-28 | — | — | CN | disclosed |
| CN-1561334-A | Indole derivatives as COXII inhibitors | HOFFMANN LA ROCHE (CH) | 2005-01-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175599-A1 | FAAH Inhibitors | FAAH, FAAH2, ASAH1 | RAB9A 1384/4885NPC1 537/4885ALDH1A1 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.