Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21994422 | 0.79 | ENPP2 (0.56) | ENPP2 | |
| SCHEMBL1303307 | 0.76 | LPL (0.48) | ENPP2 | |
| SCHEMBL15940842 | 0.74 | ENPP2 (0.50) | ENPP2 | |
| SCHEMBL29955816 | 0.73 | ENPP2 (0.32) | ENPP2 | |
| SCHEMBL931865 | 0.73 | ENPP2 (0.32) | ENPP2 | |
| SCHEMBL9951567 | 0.73 | HTT (0.36) | — | |
| SCHEMBL19009019 | 0.73 | THRB (0.34) | ENPP2 | |
| Hydrochloric Acid SCHEMBL29955592 | 0.72 | ENPP2 (0.48) | ENPP2 | |
| SCHEMBL2067301 | 0.71 | CYP11B2 (0.42) | ENPP2 | |
| SCHEMBL17847176 | 0.71 | GABRA1 (0.34) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655378-A1 | COMPOUNDS AND THEIR USE AS BACE INHIBITORS | AstraZeneca AB (SE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087237-A1 | COMPOUNDS AND THEIR USE AS BACE INHIBITORS | ASTRAZENECA AB (SE) | 2012-06-28 | — | — | WO | disclosed |