Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953657 | 0.86 | HCAR1 (0.56) | HCAR1ALDH1A1L3MBTL1MEN1LMNA | |
| SCHEMBL9954671 | 0.85 | HCAR1 (0.52) | HCAR1L3MBTL1LMNAPDE4DTDO2 | |
| SCHEMBL9953833 | 0.83 | HCAR1 (0.58) | HCAR1L3MBTL1PI4KAPIK3CGPDE4D | |
| SCHEMBL9953432 | 0.81 | HCAR1 (0.55) | HCAR1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL9954747 | 0.81 | HCAR1 (0.53) | HCAR1ALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL9954001 | 0.81 | PDE4D (0.56) | HCAR1ALDH1A1L3MBTL1PI4KAPIK3CG | |
| SCHEMBL9953324 | 0.79 | HCAR1 (0.50) | HCAR1PI4KAPIK3CGKDM4E | |
| SCHEMBL9954915 | 0.79 | PI4KA (0.47) | HCAR1ALDH1A1L3MBTL1PI4KAPIK3CG | |
| SCHEMBL9954341 | 0.79 | L3MBTL1 (0.51) | ALDH1A1L3MBTL1MEN1LMNAKMT2A | |
| SCHEMBL9954066 | 0.78 | PI4KA (0.46) | PI4KAPIK3CGPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |