Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPD | P32754 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954370 | 0.86 | L3MBTL1 (0.51) | L3MBTL1TP53LMNAMEN1KMT2A | |
| SCHEMBL9953833 | 0.85 | HCAR1 (0.58) | L3MBTL1 | |
| SCHEMBL9954001 | 0.84 | PDE4D (0.56) | L3MBTL1TP53LMNAMAPTHPD | |
| SCHEMBL9954671 | 0.83 | HCAR1 (0.52) | L3MBTL1LMNAHPD | |
| SCHEMBL9954747 | 0.81 | HCAR1 (0.53) | TP53LMNAHPDALDH1A1 | |
| SCHEMBL9953432 | 0.81 | HCAR1 (0.55) | TP53LMNAMEN1KMT2AMAPT | |
| SCHEMBL9954915 | 0.81 | PI4KA (0.47) | L3MBTL1TP53LMNAMAPTALDH1A1 | |
| SCHEMBL9953324 | 0.79 | HCAR1 (0.50) | MAPK1 | |
| SCHEMBL9953795 | 0.79 | SMN1; SMN2 (0.55) | TP53LMNAMEN1KMT2AMAPT | |
| SCHEMBL9952676 | 0.79 | HCAR1 (0.56) | L3MBTL1LMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |