Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPD | P32754 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9955332 | 0.87 | HCAR1 (0.51) | HCAR1LMNATP53ALDH1A1HPD | |
| SCHEMBL9954671 | 0.86 | HCAR1 (0.52) | HCAR1LMNAHPD | |
| SCHEMBL9954001 | 0.85 | PDE4D (0.56) | HCAR1LMNATP53ALDH1A1HPD | |
| SCHEMBL9953432 | 0.85 | HCAR1 (0.55) | HCAR1LMNATP53ALDH1A1POLB | |
| SCHEMBL9953324 | 0.82 | HCAR1 (0.50) | HCAR1KDM4E | |
| SCHEMBL9954915 | 0.81 | PI4KA (0.47) | HCAR1LMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL9952676 | 0.81 | HCAR1 (0.56) | HCAR1LMNAALDH1A1POLBKDM4E | |
| SCHEMBL9954341 | 0.81 | L3MBTL1 (0.51) | LMNATP53ALDH1A1HPD | |
| SCHEMBL9954830 | 0.81 | HCAR1 (0.43) | HCAR1 | |
| SCHEMBL9953833 | 0.79 | HCAR1 (0.58) | HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |