Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.50 |
| ▸ | PI4KA | P42356 | 7/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954094 | 0.87 | HCAR1 (0.51) | HCAR1PI4KAPIK3CGCA12CA1 | |
| SCHEMBL9954651 | 0.87 | POLB (0.53) | PI4KAPIK3CGCA12CA1CA2 | |
| SCHEMBL9953665 | 0.87 | TGM2 (0.45) | PI4KAPIK3CG | |
| SCHEMBL9955586 | 0.87 | HPD (0.44) | HCAR1PI4KAPIK3CGCA12CA1 | |
| SCHEMBL9953795 | 0.85 | SMN1; SMN2 (0.55) | PI4KAPIK3CGKDM4E | |
| SCHEMBL9954423 | 0.85 | POLB (0.41) | PI4KAPIK3CGCA12CA1CA2 | |
| SCHEMBL9953800 | 0.85 | POLB (0.41) | HCAR1PI4KAPIK3CGCA12CA1 | |
| SCHEMBL9953556 | 0.84 | CA12 (0.42) | HCAR1CA12CA1CA2CA9 | |
| SCHEMBL9954066 | 0.84 | PI4KA (0.46) | PI4KAPIK3CGCA12CA1CA2 | |
| SCHEMBL9953024 | 0.84 | CA12 (0.52) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |