Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | STK10 | O94804 | 1/20 | 0.33 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | CBLB | Q13191 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952788 | 0.86 | HSD11B1 (0.33) | P2RX7HSD11B1BRD4NPC1RAB9A | |
| SCHEMBL9953917 | 0.85 | CBLB (0.36) | HSD11B1BRD4NPC1RAB9ASCD | |
| SCHEMBL9952936 | 0.83 | NPC1 (0.35) | HSD11B1NPC1RAB9ASCDOPRK1 | |
| SCHEMBL9952864 | 0.76 | HTR2C (0.37) | BRD4NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL9952128 | 0.74 | HSD11B1 (0.32) | HSD11B1BRD4SCDOPRK1RORC | |
| SCHEMBL7845615 | 0.73 | HSD11B1 (0.60) | HSD11B1BRD4KDM4EALDH1A1 | |
| SCHEMBL9952318 | 0.73 | ALDH1A1 (0.35) | BRD4NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL9952650 | 0.72 | P2RX7 (0.36) | P2RX7NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL9953831 | 0.71 | OPRK1 (0.34) | HSD11B1NPC1RAB9ASCDOPRK1 | |
| SCHEMBL3722934 | 0.69 | BRD4 (0.37) | BRD4NPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655337-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | Sumitomo Chemical Company Limited (JP) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012086848-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-28 | — | — | WO | disclosed |