Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 10/20 | 0.38 |
| ▸ | CNR1 | P21554 | 7/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953313 | 0.96 | ALPL (0.55) | ALPLCNR2CNR1DGAT1AAK1 | |
| SCHEMBL23585583 | 0.91 | ALPL (0.51) | ALPLCNR2CNR1DGAT1AAK1 | |
| SCHEMBL9953817 | 0.84 | ALPL (0.56) | ALPLALDH1A1SMN1; SMN2HTT | |
| SCHEMBL14317989 | 0.84 | ALPL (0.59) | ALPLDGAT1AAK1PIK3R1PIK3CA | |
| SCHEMBL9954287 | 0.83 | ALPL (0.55) | ALPLALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9954766 | 0.82 | ALPL (0.56) | ALPLDGAT1PIK3CAALDH1A1SMN1; SMN2 | |
| SCHEMBL9953730 | 0.82 | ALPL (0.57) | ALPLDGAT1AAK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9953535 | 0.82 | ALPL (0.57) | ALPLDGAT1AAK1PIK3R1PIK3CA | |
| SCHEMBL9955177 | 0.81 | ALPL (0.56) | ALPLDGAT1AAK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9954091 | 0.80 | ALPL (0.61) | ALPLDGAT1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |