Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14247605 | 0.85 | PDGFRB (0.48) | ALPLLMNAPOLBDGAT1KMT2A | |
| SCHEMBL10289073 | 0.85 | ALPL (0.56) | ALPLALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL14317989 | 0.85 | ALPL (0.59) | ALPLALDH1A1SMN1; SMN2POLBDGAT1 | |
| SCHEMBL798423 | 0.84 | ALPL (0.76) | ALPLALDH1A1LMNAKMT2A | |
| SCHEMBL9953535 | 0.83 | ALPL (0.57) | ALPLSMN1; SMN2DGAT1 | |
| SCHEMBL9953313 | 0.82 | ALPL (0.55) | ALPLALDH1A1DGAT1 | |
| SCHEMBL31113862 | 0.82 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2LMNACYP1A2CYP2C19 | |
| SCHEMBL9955177 | 0.82 | ALPL (0.56) | ALPLALDH1A1SMN1; SMN2DGAT1MEN1 | |
| SCHEMBL31113866 | 0.82 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2LMNACYP1A2CYP2C19 | |
| SCHEMBL9955039 | 0.81 | ALPL (0.54) | ALPLALDH1A1POLBDGAT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |