Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.57 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953888 | 0.91 | ALPL (0.56) | ALPLDGAT1AAK1GSK3AGSK3B | |
| SCHEMBL14317989 | 0.88 | ALPL (0.59) | ALPLDGAT1AAK1GSK3AGSK3B | |
| SCHEMBL9955177 | 0.85 | ALPL (0.56) | ALPLDGAT1AAK1GSK3AGSK3B | |
| SCHEMBL798817 | 0.85 | ALPL (0.60) | ALPLDGAT1AAK1GSK3AGSK3B | |
| SCHEMBL9953472 | 0.84 | ALPL (0.62) | ALPLDGAT1AAK1GSK3AGSK3B | |
| SCHEMBL9953313 | 0.84 | ALPL (0.55) | ALPLDGAT1AAK1 | |
| SCHEMBL9954582 | 0.84 | ALPL (0.55) | ALPLDGAT1AAK1GSK3AGSK3B | |
| SCHEMBL14317979 | 0.83 | ALPL (0.56) | ALPLDGAT1AAK1GSK3AGSK3B | |
| SCHEMBL9954091 | 0.83 | ALPL (0.61) | ALPLDGAT1SMN1; SMN2 | |
| SCHEMBL9952979 | 0.82 | ALPL (0.53) | ALPLDGAT1AAK1NAMPTPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |