Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954899 | 0.90 | SMN1; SMN2 (0.47) | LMNATP53CA12CA1CA2 | |
| SCHEMBL9953908 | 0.88 | TP53 (0.47) | ACP1LMNATP53CA12CA1 | |
| SCHEMBL9953860 | 0.87 | CYP1A2 (0.42) | LMNATP53CA12CA1CA2 | |
| SCHEMBL9953858 | 0.87 | MEN1 (0.41) | LMNATP53CA12CA1CA2 | |
| SCHEMBL9953706 | 0.84 | MITF (0.46) | VNN1ACP1NPBWR1MCHR1 | |
| SCHEMBL9954787 | 0.83 | MEN1 (0.44) | LMNATP53CA12CA1CA2 | |
| SCHEMBL9953937 | 0.82 | MEN1 (0.46) | LMNATP53CA12CA1CA2 | |
| SCHEMBL9954411 | 0.82 | CA12 (0.44) | LMNATP53CA12CA1CA2 | |
| SCHEMBL9953750 | 0.82 | CYP3A4 (0.44) | ACP1LMNATP53CA12CA1 | |
| SCHEMBL9955119 | 0.81 | MAPT (0.46) | ACP1LMNATP53MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |