Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954815 | 0.90 | ACP1 (0.47) | ACP1SCD | |
| SCHEMBL9954899 | 0.90 | SMN1; SMN2 (0.47) | CYP1A2 | |
| SCHEMBL9953858 | 0.89 | MEN1 (0.41) | CYP1A2 | |
| SCHEMBL9953908 | 0.88 | TP53 (0.47) | ACP1CYP1A2 | |
| SCHEMBL9953860 | 0.87 | CYP1A2 (0.42) | CYP1A2 | |
| SCHEMBL9953199 | 0.84 | VNN1 (0.46) | ACP1VNN1NPBWR1MCHR1 | |
| SCHEMBL9954573 | 0.84 | USP1 (0.47) | ACP1CYP1A2 | |
| SCHEMBL9954411 | 0.84 | CA12 (0.44) | — | |
| SCHEMBL9953654 | 0.83 | TP53 (0.42) | CYP1A2 | |
| SCHEMBL9954787 | 0.83 | MEN1 (0.44) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |