Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 10/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952654 | 0.83 | PIK3CD (0.40) | PIK3CD | |
| SCHEMBL14753976 | 0.82 | PIK3CD (0.41) | PIK3CD | |
| SCHEMBL16945978 | 0.81 | PIK3CD (0.44) | PIK3CD | |
| SCHEMBL9952276 | 0.79 | ALDH1A1 (0.33) | PIK3CD | |
| SCHEMBL9929335 | 0.76 | PIK3CD (0.36) | PIK3CD | |
| SCHEMBL28712875 | 0.75 | ALDH1A1 (0.39) | PIK3CD | |
| SCHEMBL14742475 | 0.74 | CHRNB2 (0.34) | PIK3CD | |
| SCHEMBL9953206 | 0.74 | IMPDH2 (0.34) | PIK3CD | |
| SCHEMBL9952859 | 0.71 | PIK3CD (0.36) | PIK3CD | |
| SCHEMBL9929221 | 0.71 | PIK3CD (0.60) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655374-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | Incyte Corporation (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087881-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |