Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953447 | 0.88 | SHMT2 (0.49) | SHMT2MEN1KMT2AALPLNPC1 | |
| SCHEMBL806771 | 0.88 | SHMT2 (0.55) | SHMT2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL9954777 | 0.87 | PIK3CD (0.56) | SHMT2MEN1KMT2AALPLNPC1 | |
| SCHEMBL806782 | 0.86 | SMN1; SMN2 (0.54) | SHMT2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL9953017 | 0.84 | PI4KA (0.53) | LMNAPIK3R1PIK3CAPIK3CGPIK3C3 | |
| SCHEMBL30902109 | 0.84 | PI4KA (0.53) | LMNAPIK3R1PIK3CAPIK3CGPIK3C3 | |
| SCHEMBL16996888 | 0.84 | PIK3C3 (0.60) | MEN1KMT2APIK3R1PIK3CAPIK3CG | |
| SCHEMBL806765 | 0.82 | LMNA (0.53) | SHMT2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL806788 | 0.80 | POLB (0.53) | SHMT2ALDH1A1MEN1KMT2APKM | |
| SCHEMBL15211892 | 0.80 | ALPL (0.72) | LMNAALDH1A1SMN1; SMN2ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |