Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 6/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9959889 | 0.74 | DGAT1 (0.35) | RAB9ANPC1MAPT | |
| SCHEMBL9952722 | 0.73 | HIF1A (0.40) | ALDH1A1PDE10ALRRK2 | |
| SCHEMBL31182088 | 0.72 | RAB9A (0.38) | RAB9ANPC1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL30035295 | 0.72 | RAB9A (0.38) | RAB9ANPC1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL30961444 | 0.72 | PDE10A (0.43) | RAB9ANPC1EPHX2L3MBTL1KDM4E | |
| SCHEMBL10289055 | 0.72 | GPR35 (0.48) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL20265710 | 0.71 | MALT1 (0.35) | EPHX2TYK2PPARA | |
| SCHEMBL25212088 | 0.70 | BDKRB1 (0.35) | EPHX2LRRK2 | |
| SCHEMBL29818560 | 0.70 | BDKRB1 (0.35) | EPHX2LRRK2 | |
| SCHEMBL9953876 | 0.70 | ALDH1A1 (0.32) | RAB9ANPC1ALDH1A1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |