Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647836 | 0.81 | CA4 (0.36) | LTA4HTP53CA4TSHRESR1 | |
| SCHEMBL647415 | 0.81 | CA4 (0.36) | LTA4HTP53CA4TSHRESR1 | |
| SCHEMBL10570173 | 0.80 | LTA4H (0.38) | LTA4HTP53TSHRCALM1ALDH1A1 | |
| SCHEMBL705542 | 0.79 | CA4 (0.35) | LTA4HTP53CA4ESR1ESR2 | |
| SCHEMBL1262887 | 0.77 | CA4 (0.33) | LTA4HCA4ESR1ESR2POLB | |
| SCHEMBL15912070 | 0.77 | ESR1 (0.35) | LTA4HCA4TSHRESR1ESR2 | |
| SCHEMBL4079195 | 0.77 | CA4 (0.33) | LTA4HCA4ESR1ESR2POLB | |
| SCHEMBL4076791 | 0.77 | TRPA1 (0.33) | LTA4HCA4TSHRESR1ESR2 | |
| SCHEMBL27996306 | 0.77 | CA4 (0.35) | LTA4HTP53CA4ESR1ESR2 | |
| SCHEMBL703898 | 0.77 | CA4 (0.33) | LTA4HCA4ESR1ESR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013192404-A1 | POLYHETEROSILOXANE COMPOSITION | DOW CORNING CORPORATION (US) | 2013-12-27 | — | — | WO | disclosed |
| US-20130284978-A1 | Polyheterosiloxane Composition Including Lanthanide Metal | DOW CORNING CORPORATION (US) | 2013-10-31 | — | — | US | disclosed |
| EP-2655482-A1 | POLYHETEROSILOXANE COMPOSITION INCLUDING LANTHANIDE METAL | Dow Corning Corporation (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012088439-A1 | POLYHETEROSILOXANE COMPOSITION INCLUDING LANTHANIDE METAL | DOW CORNING CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |