Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 8/20 | 0.45 |
| ▸ | CA1 | P00915 | 8/20 | 0.45 |
| ▸ | CA2 | P00918 | 8/20 | 0.45 |
| ▸ | CA9 | Q16790 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953877 | 0.86 | POLB (0.54) | POLBMAPTATMCA12CA1 | |
| SCHEMBL9953024 | 0.83 | CA12 (0.52) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL9953324 | 0.80 | HCAR1 (0.50) | CA12CA1CA2CA9PI4KA | |
| SCHEMBL9954651 | 0.79 | POLB (0.53) | POLBCA12CA1CA2CA9 | |
| SCHEMBL9954094 | 0.79 | HCAR1 (0.51) | POLBMAPTATMCA12CA1 | |
| SCHEMBL9955556 | 0.77 | CA12 (0.47) | POLBCA12CA1CA2CA9 | |
| SCHEMBL9953800 | 0.77 | POLB (0.41) | POLBCA12CA1CA2CA9 | |
| SCHEMBL9953795 | 0.77 | SMN1; SMN2 (0.55) | POLBMAPTALDH1A1PI4KAPIK3CG | |
| SCHEMBL9953556 | 0.76 | CA12 (0.42) | POLBCA12CA1CA2CA9 | |
| SCHEMBL9954066 | 0.76 | PI4KA (0.46) | POLBCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |