Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 11/20 | 0.42 |
| ▸ | CA1 | P00915 | 11/20 | 0.42 |
| ▸ | CA2 | P00918 | 11/20 | 0.42 |
| ▸ | CA9 | Q16790 | 11/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954651 | 0.86 | POLB (0.53) | CA12CA1CA2CA9POLB | |
| SCHEMBL9955025 | 0.85 | ESR2 (0.41) | CA12CA1CA2CA9POLB | |
| SCHEMBL9953324 | 0.84 | HCAR1 (0.50) | CA12CA1CA2CA9HCAR1 | |
| SCHEMBL9954094 | 0.83 | HCAR1 (0.51) | CA12CA1CA2CA9HCAR1 | |
| SCHEMBL9954066 | 0.82 | PI4KA (0.46) | CA12CA1CA2CA9POLB | |
| SCHEMBL9954423 | 0.81 | POLB (0.41) | CA12CA1CA2CA9POLB | |
| SCHEMBL9953024 | 0.80 | CA12 (0.52) | CA12CA1CA2CA9 | |
| SCHEMBL9954672 | 0.79 | TDO2 (0.52) | POLB | |
| SCHEMBL9953800 | 0.78 | POLB (0.41) | CA12CA1CA2CA9HCAR1 | |
| SCHEMBL9953665 | 0.78 | TGM2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |