SCHEMBL995458

SCHEMBL995458

C=CC(=O)C1CCOC(=O)CC1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.34
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1366482 0.77 TSHR (0.40) ALDH1A1LMNATP53TSHRCA1
SCHEMBL25936320 0.74 THRA (0.47) THRATHRB
SCHEMBL15198301 0.74 LMNA (0.39) ALDH1A1LMNATP53TSHRCA1
SCHEMBL2117075 0.71 ALDH1A1 (0.31) ALDH1A1LMNATP53TSHRCA1
SCHEMBL2854651 0.71 ALDH1A1 (0.42) ALDH1A1LMNATP53TSHRCA1
SCHEMBL4713780 0.71
SCHEMBL10775241 0.71 THRA (0.61) THRATHRBALDH1A1LMNATSHR
SCHEMBL15509364 0.70
SCHEMBL9308848 0.69 THRA (0.39) THRATHRB
SCHEMBL23035475 0.69 THRA (0.32) THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2456764-B1 A METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL)ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL)ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME SSENS B V (NL) 2016-03-30 EP disclosed
US-8927196-B2 Method of making an (alkyl)acryloyl polycarbonate SSENS B.V. (NL) 2015-01-06 US disclosed
US-20120294845-A1 METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL) ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL) ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME SSENS B.V. (NL) 2012-11-22 US disclosed
CN-102712616-A A method of making a polymer preferably an (alkyl) acryloyl polycarbonate, the polymer and (alkyl)acryloyl polycarbonate obtained, and a biodevice comprising same SSENS B V 2012-10-03 CN disclosed
EP-1984462-B1 ELECTROGRAFTING METHOD FOR FORMING AND REGULATING A STRONG ADHERENT NANOSTRUCTURED POLYMER COATING UNIV LIEGE (BE) 2012-07-04 EP disclosed
EP-2456764-A1 A METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL)ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL)ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME Ssens B.V. (NL) 2012-05-30 EP disclosed
WO-2011009478-A1 A METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL)ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL)ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME SSENS B.V. (NL) 2011-01-27 WO disclosed
US-20090020431-A1 Electrografting Method for Forming and Regulating a Strong Adherent Nanostructured Polymer Coating UNIVERSITE DE LIEGE (BE) 2009-01-22 US disclosed
EP-1984462-A1 ELECTROGRAFTING METHOD FOR FORMING AND REGULATING A STRONG ADHERENT NANOSTRUCTURED POLYMER COATING Université de Liège (BE) 2008-10-29 EP disclosed
WO-2007090779-A1 ELECTROGRAFTING METHOD FOR FORMING AND REGULATING A STRONG ADHERENT NANOSTRUCTURED POLYMER COATING UNIVERSITE DE LIEGE (BE) 2007-08-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120294845-A1 METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL) ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL) ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME TET3, ALKBH3, ALKBH1 THRA 4629/4885THRB 4856/4885ALDH1A1 2240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.