Sugi Predict

Sugi Predict / Compounds / SCHEMBL1366482

SCHEMBL1366482

SCHEMBL1366482

O=C1CCC(C(=O)O)CCO1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 5/20 0.40
▸ LMNA P02545 3/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ TP53 P04637 1/20 0.40
▸ CA1 P00915 2/20 0.38
▸ CA9 Q16790 2/20 0.38
▸ GABRP O00591 3/20 0.37
▸ GABRD O14764 3/20 0.37
▸ GABRA1 P14867 3/20 0.37
▸ GABRB1 P18505 3/20 0.37
▸ GABRG2 P18507 3/20 0.37
▸ GABRB3 P28472 3/20 0.37
▸ GABRA5 P31644 3/20 0.37
▸ GABRA3 P34903 3/20 0.37
▸ GABRA2 P47869 3/20 0.37
▸ GABRB2 P47870 3/20 0.37
▸ GABRA4 P48169 3/20 0.37
▸ GABRE P78334 3/20 0.37
▸ GABRA6 Q16445 3/20 0.37
▸ GABRG1 Q8N1C3 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9858426 0.81 GABRP (0.38) TSHRLMNAALDH1A1TP53CA1
SCHEMBL4749566 0.81 CYP1A2 (0.39) TSHRLMNAALDH1A1TP53GABRP
SCHEMBL28312745 0.77 CA1 (0.57) TSHRLMNAALDH1A1TP53CA1
SCHEMBL995458 0.77 THRA (0.39) TSHRLMNAALDH1A1TP53CA1
SCHEMBL15198301 0.76 LMNA (0.39) TSHRLMNAALDH1A1TP53CA1
SCHEMBL15509364 0.76 — —
SCHEMBL27730575 0.73 ALDH1A1 (0.44) TSHRALDH1A1MEN1KMT2ANPC1
SCHEMBL6126 0.72 GABRP (0.46) TSHRLMNAGABRPGABRDGABRA1
SCHEMBL15705536 0.71 — —
SCHEMBL10000010 0.71 ALDH1A1 (0.43) TSHRLMNAALDH1A1TP53CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114349944-A Polycaprolactone block copolymer and preparation method thereof 中石化南京化工研究院有限公司 2022-04-15 — — CN claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 — — US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 — — US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 — — US claimed
CN-114349944-B Polycaprolactone block copolymer and preparation method thereof 中石化南京化工研究院有限公司 2023-12-05 — — CN disclosed
CN-114349944-A Polycaprolactone block copolymer and preparation method thereof 中石化南京化工研究院有限公司 2022-04-15 — — CN disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 — — US disclosed
US-8067136-B2 Charge control agent, toner, image forming method, and image forming apparatus CANON KABUSHIKI KAISHA (JP) 2011-11-29 — — US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 — — US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 — — US disclosed
US-20090202927-A1 Charge control agent, toner, image forming method, and image forming apparatus CANON KABUSHIKI KAISHA (JP) 2009-08-13 — — US disclosed
US-7510813-B2 Resin-coated carrier for electrophotographic developer CANON KABUSHIKI KAISHA (JP) 2009-03-31 — — US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 — — US disclosed
EP-1774410-B1 CHARGE CONTROL AGENT, TONER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS CANON KK (JP) 2008-11-19 — — EP disclosed
EP-1774410-A1 CHARGE CONTROL AGENT, TONER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS Canon Kabushiki Kaisha (JP) 2007-04-18 — — EP disclosed
US-20050287484-A1 Resin-coated carrier for electrophotographic developer CANON KABUSHIKI KAISHA (JP) 2005-12-29 — — US disclosed
WO-2005121904-A1 CHARGE CONTROL AGENT, TONER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2005-12-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 TSHR 4385/4885LMNA 1561/4885ALDH1A1 1901/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB TSHR 4263/4885LMNA 72/4885ALDH1A1 4765/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA TSHR 2885/4885LMNA 833/4885ALDH1A1 1510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.