Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | CASP7 | P55210 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9955387 | 0.76 | TDO2 (0.50) | ALDH1A1HSD17B10CASP7TSHRKDM4E | |
| SCHEMBL6975203 | 0.75 | KDM4E (0.72) | ALDH1A1HSD17B10L3MBTL1RXFP1KDM4E | |
| SCHEMBL27192153 | 0.72 | HSD17B10 (0.47) | ALDH1A1HSD17B10CASP7KDM4EMAPT | |
| SCHEMBL8372087 | 0.71 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1RXFP1KDM4EGAA | |
| SCHEMBL9952861 | 0.71 | TDO2 (0.46) | ALDH1A1HSD17B10CASP7TSHRL3MBTL1 | |
| SCHEMBL1432105 | 0.71 | LMNA (0.59) | ALDH1A1HSD17B10KDM4EMAPTMEN1 | |
| SCHEMBL30969118 | 0.70 | ALDH1A1 (0.51) | ALDH1A1HSD17B10CASP7L3MBTL1RXFP1 | |
| SCHEMBL27329825 | 0.69 | LMNA (0.71) | ALDH1A1HSD17B10CASP7TSHRKDM4E | |
| SCHEMBL885660 | 0.67 | KMO (0.52) | ALDH1A1HSD17B10MAPTLMNAKIF11 | |
| SCHEMBL3342878 | 0.66 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CASP7L3MBTL1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |