Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790432 | 0.88 | PIK3CA (0.45) | PDGFRBKDRALPLSLC40A1PIK3CG | |
| SCHEMBL9955288 | 0.86 | PIK3CG (0.52) | PDGFRBKDRALPLSLC40A1PIK3CG | |
| SCHEMBL29555684 | 0.85 | PIK3CD (0.57) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3115744 | 0.85 | PIK3CD (0.57) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL807318 | 0.84 | SLC40A1 (0.38) | PDGFRBKDRSLC40A1PIK3CGPIK3CD | |
| SCHEMBL790824 | 0.83 | ALPL (0.56) | PDGFRBKDRALPLSLC40A1PIK3CG | |
| SCHEMBL29556839 | 0.83 | ALPL (0.56) | PDGFRBKDRALPLSLC40A1PIK3CG | |
| SCHEMBL789981 | 0.81 | ALPL (0.48) | PDGFRBKDRALPLSLC40A1PIK3CG | |
| SCHEMBL791429 | 0.81 | ALPL (0.47) | PDGFRBKDRALPLSLC40A1PIK3CG | |
| SCHEMBL14247499 | 0.78 | POLB (0.55) | PDGFRBKDRALPLPIK3CGCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |