Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271334 | 0.79 | KMT2A (0.32) | — | |
| SCHEMBL7271607 | 0.79 | GRN (0.35) | — | |
| SCHEMBL10097959 | 0.78 | DPP4 (0.30) | — | |
| SCHEMBL20767316 | 0.78 | SLC6A3 (0.41) | — | |
| SCHEMBL1008191 | 0.75 | MDM2 (0.40) | — | |
| SCHEMBL1008766 | 0.72 | RAPGEF3 (0.40) | — | |
| SCHEMBL166050 | 0.72 | HDAC4 (0.41) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL15527543 | 0.72 | EDNRB (0.34) | — | |
| SCHEMBL1005803 | 0.71 | PPARD (0.33) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL6097343 | 0.68 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9066945-B2 | Ectoparasiticidal active substance combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-9066945-B2 | Ectoparasiticidal active substance combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-9066945-B2 | Ectoparasiticidal active substance combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-20140179623-A1 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
| US-20140179623-A1 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
| US-20140179623-A1 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
| EP-2654425-A2 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | Bayer Intellectual Property GmbH (DE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012084852-A2 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER ANIMAL HEALTH GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179623-A1 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | EPX, CAT, PIGO | PDK1 888/4885PDK2 228/4885PDK3 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.