Sugi Predict

Sugi Predict / Compounds / SCHEMBL9956435

SCHEMBL9956435

SCHEMBL9956435

Clc1nc(-c2cc(-c3ccccc3)cc(-c3ccccc3)c2)cc(-c2cc(-c3ccccc3)cc(-c3ccccc3)c2)n1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 9/20 0.79
▸ MEN1 O00255 8/20 0.79
▸ ALDH1A1 P00352 6/20 0.79
▸ HPGD P15428 4/20 0.79
▸ L3MBTL1 Q9Y468 3/20 0.79
▸ SMN1; SMN2 Q16637 2/20 0.79
▸ KDM4E B2RXH2 6/20 0.63
▸ MAPT P10636 6/20 0.63
▸ TDP1 Q9NUW8 2/20 0.63
▸ LMNA P02545 2/20 0.52
▸ GLA P06280 1/20 0.52
▸ ADORA2A P29274 1/20 0.48
▸ ADORA1 P30542 1/20 0.48
▸ HSP90AA1 P07900 1/20 0.46
▸ HSP90AB1 P08238 1/20 0.46
▸ CYP19A1 P11511 1/20 0.46
▸ AGTR1 P30556 1/20 0.44
▸ TSHR P16473 1/20 0.44
▸ ATM Q13315 1/20 0.44
▸ CTRC Q99895 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31448341 0.98 MEN1 (0.83) KMT2AMEN1ALDH1A1HPGDL3MBTL1
SCHEMBL13172570 0.94 MEN1 (0.77) KMT2AMEN1ALDH1A1HPGDL3MBTL1
SCHEMBL13172350 0.92 MEN1 (0.80) KMT2AMEN1ALDH1A1HPGDL3MBTL1
SCHEMBL21029434 0.90 KMT2A (0.64) KMT2AMEN1ALDH1A1HPGDL3MBTL1
SCHEMBL15284207 0.89 MEN1 (0.76) KMT2AMEN1ALDH1A1HPGDL3MBTL1
SCHEMBL9881174 0.89 MEN1 (0.76) KMT2AMEN1ALDH1A1HPGDL3MBTL1
SCHEMBL24212278 0.89 MEN1 (0.91) KMT2AMEN1ALDH1A1HPGDL3MBTL1
SCHEMBL16161050 0.89 MEN1 (0.91) KMT2AMEN1ALDH1A1HPGDL3MBTL1
SCHEMBL13728744 0.89 MEN1 (0.91) KMT2AMEN1ALDH1A1HPGDL3MBTL1
SCHEMBL10051514 0.89 MEN1 (0.91) KMT2AMEN1ALDH1A1HPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12035625-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2024-07-09 — — US disclosed
US-12035625-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2024-07-09 — — US disclosed
US-20230403927-A1 AROMATIC COMPOUNDS UDC IRELAND LTD (IE) 2023-12-14 — — US disclosed
US-20230403927-A1 AROMATIC COMPOUNDS UDC IRELAND LTD (IE) 2023-12-14 — — US disclosed
US-11800787-B2 Metal complexes UDC IRELAND LIMITED (IE) 2023-10-24 — — US disclosed
US-11800787-B2 Metal complexes UDC IRELAND LIMITED (IE) 2023-10-24 — — US disclosed
EP-3880682-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-14 — — EP disclosed
US-11581497-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-02-14 — — US disclosed
US-11535619-B2 Hexacyclic heteroaromatic compounds for electronic devices MERCK PATENT GMBH (DE) 2022-12-27 — — US disclosed
US-11495751-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-11-08 — — US disclosed
US-20150337197-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-11-26 — — US disclosed
US-20150337197-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-11-26 — — US disclosed
WO-2014106524-A2 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2014-07-10 — — WO disclosed
WO-2014094963-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-06-26 — — WO disclosed
EP-2655339-A1 ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND E.I. Du Pont De Nemours And Company (US) 2013-10-30 — — EP disclosed
US-20130256646-A1 ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND E I DU PONT DE NEMOURS AND COMPANY (US) 2013-10-03 — — US disclosed
US-20130256646-A1 ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND E I DU PONT DE NEMOURS AND COMPANY (US) 2013-10-03 — — US disclosed
US-20130256646-A1 ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND E I DU PONT DE NEMOURS AND COMPANY (US) 2013-10-03 — — US disclosed
WO-2012088192-A1 ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-28 — — WO disclosed
WO-2012088192-A1 ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230403927-A1 AROMATIC COMPOUNDS TYR, CTCF, MITF KMT2A 1055/4885MEN1 2141/4885ALDH1A1 1461/4885
US-11495751-B2 Materials for organic electroluminescent devices OR10J3, EPCAM, L1CAM KMT2A 1511/4885MEN1 1294/4885ALDH1A1 473/4885
US-11581497-B2 Materials for organic electroluminescent devices OR10J3, EPCAM, L1CAM KMT2A 1833/4885MEN1 1639/4885ALDH1A1 504/4885
US-11800787-B2 Metal complexes AP1M1, SOD1, AP3M1 KMT2A 2648/4885MEN1 766/4885ALDH1A1 3771/4885
US-11535619-B2 Hexacyclic heteroaromatic compounds for electronic devices ETV6, CYP2J2, CYP2D6 KMT2A 735/4885MEN1 2590/4885ALDH1A1 647/4885
US-20150337197-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, EML4, L1CAM KMT2A 2434/4885MEN1 1571/4885ALDH1A1 405/4885
US-12035625-B2 Materials for organic electroluminescent devices ZYX, RER1, AOC2 KMT2A 1372/4885MEN1 1681/4885ALDH1A1 1119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.