Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9956545 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TSHRKMT2APOLBPKM | |
| SCHEMBL11208659 | 0.81 | PPARG (0.40) | ALDH1A1TSHRKMT2AMAPTALOX15 | |
| SCHEMBL11208660 | 0.81 | PPARG (0.40) | ALDH1A1TSHRKMT2AMAPTALOX15 | |
| SCHEMBL27205635 | 0.80 | EPHX2 (0.32) | — | |
| SCHEMBL31210264 | 0.77 | PPARG (0.49) | ALDH1A1KMT2APOLBPKMBLM | |
| SCHEMBL31210275 | 0.77 | PPARG (0.49) | ALDH1A1KMT2APOLBPKMBLM | |
| Benzene SCHEMBL27792631 | 0.76 | CPB2 (0.35) | ALOX15SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30634622 | 0.76 | CPB2 (0.34) | SMN1; SMN2 | |
| SCHEMBL3378642 | 0.76 | CPB2 (0.34) | SMN1; SMN2 | |
| SCHEMBL669444 | 0.76 | CPB2 (0.34) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11397186-B2 | Methods for covalently binding a cell surface protein and a ligand | UNIVERSITEIT GENT (BE) | 2022-07-26 | — | — | US | disclosed |
| US-11053279-B2 | Methods for the site-selective coupling of a first agent to a second agent | UNIVERSITEIT GENT (BE) | 2021-07-06 | — | — | US | disclosed |
| US-20210018512-A1 | METHODS FOR COVALENTLY BINDING A CELL SURFACE PROTEIN AND A LIGAND | UNIVERSITEIT GENT (BE) | 2021-01-21 | — | — | US | disclosed |
| US-10753944-B2 | Methods for covalently binding a cell surface protein and a ligand | UNIVERSITEIT GENT (BE) | 2020-08-25 | — | — | US | disclosed |
| EP-3313858-B1 | METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT | UNIV GENT (BE) | 2019-09-25 | — | — | EP | disclosed |
| EP-3423837-A1 | METHODS FOR COVALENTLY BINDING A CELL SURFACE PROTEIN AND A LIGAND | Universiteit Gent (BE) | 2019-01-09 | — | — | EP | disclosed |
| US-20190002494-A1 | METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT | UNIVERSITEIT GENT (BE) | 2019-01-03 | — | — | US | disclosed |
| EP-3313858-A1 | METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT | Universiteit Gent (BE) | 2018-05-02 | — | — | EP | disclosed |
| EP-2655395-B1 | METHOD FOR CROSS-LINKING PEPTIDES | UNIV GENT (BE) | 2018-03-07 | — | — | EP | disclosed |
| US-9708363-B2 | Method for cross-linking peptides | UNIVERSITEIT GENT (BE) | 2017-07-18 | — | — | US | disclosed |
| WO-2017001204-A1 | METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT | UNIVERSITEIT GENT (BE) | 2017-01-05 | — | — | WO | disclosed |
| US-20160244481-A1 | METHOD FOR CROSS-LINKING PEPTIDES | UNIVERSITEIT GENT (BE) | 2016-08-25 | — | — | US | disclosed |
| US-9290537-B2 | Method for cross-linking peptides | UNIVERSITEIT GENT (BE) | 2016-03-22 | — | — | US | disclosed |
| US-20130289239-A1 | METHOD FOR CROSS-LINKING PEPTIDES | UNIVERSITEIT GENT (BE) | 2013-10-31 | — | — | US | disclosed |
| EP-2655395-A2 | METHOD FOR CROSS-LINKING PEPTIDES | Universiteit Gent (BE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012085279-A2 | METHOD FOR CROSS-LINKING PEPTIDES | UNIVERSITEIT GENT (BE) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053279-B2 | Methods for the site-selective coupling of a first agent to a second agent | PAICS, HNMT, DPYD | ALDH1A1 715/4885TSHR 3271/4885KMT2A 1091/4885 |
| US-20160244481-A1 | METHOD FOR CROSS-LINKING PEPTIDES | PTMS, VIP, FPR2 | ALDH1A1 2712/4885TSHR 3959/4885KMT2A 4564/4885 |
| US-20130289239-A1 | METHOD FOR CROSS-LINKING PEPTIDES | PTMS, VIP, FPR2 | ALDH1A1 2712/4885TSHR 3959/4885KMT2A 4564/4885 |
| US-20190002494-A1 | METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT | PAICS, HNMT, DPYD | ALDH1A1 715/4885TSHR 3271/4885KMT2A 1091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.