Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9956730 | 0.77 | KDM4E (0.37) | KDM4ETP53MAPTALDH1A1HPGD | |
| SCHEMBL18106122 | 0.77 | KDM4E (0.42) | PARP1KDM4ETP53MAPTALDH1A1 | |
| Broxaldine SCHEMBL29888411 | 0.74 | ALOX5 (0.41) | KDM4EMAPTALDH1A1HTTLMNA | |
| Broxaldine SCHEMBL2109050 | 0.74 | ALOX5 (0.41) | KDM4EMAPTALDH1A1HTTLMNA | |
| SCHEMBL7690476 | 0.72 | NQO2 (0.50) | KDM4EMAPTHTTLMNAGAA | |
| SCHEMBL9951316 | 0.71 | KDM4E (0.49) | KDM4ETP53MAPTALDH1A1HPGD | |
| SCHEMBL18106114 | 0.69 | GAA (0.38) | KDM4EMAPTALDH1A1HPGDHTT | |
| SCHEMBL18106119 | 0.69 | MAPT (0.45) | KDM4EMAPTALDH1A1HTTLMNA | |
| SCHEMBL9951347 | 0.68 | KDM4E (0.41) | KDM4EMAPTALDH1A1HPGDHTT | |
| SCHEMBL5708950 | 0.67 | LMNA (0.60) | KDM4EMAPTALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083866-A1 | QUINOLINE DERIVATIVES AS ANTI-CANCER AGENTS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2012-06-28 | — | — | WO | disclosed |