Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9956727 | 0.77 | PARP1 (0.37) | KDM4ELMNAHTTKMT2AMEN1 | |
| SCHEMBL7690476 | 0.70 | NQO2 (0.50) | KDM4ELMNAHTTKMT2AMEN1 | |
| SCHEMBL9951347 | 0.69 | KDM4E (0.41) | KDM4ELMNAHTTKMT2AMEN1 | |
| Broxaldine SCHEMBL2109050 | 0.68 | ALOX5 (0.41) | KDM4ELMNAHTTKMT2AMEN1 | |
| Broxaldine SCHEMBL29888411 | 0.68 | ALOX5 (0.41) | KDM4ELMNAHTTKMT2AMEN1 | |
| SCHEMBL2167807 | 0.68 | CXCL8 (0.42) | KDM4ELMNAHTTKMT2AMAPT | |
| SCHEMBL9951316 | 0.68 | KDM4E (0.49) | KDM4ELMNAHTTKMT2AMEN1 | |
| SCHEMBL28554817 | 0.67 | KDM4E (0.40) | KDM4ELMNAHTTKMT2AMEN1 | |
| SCHEMBL18106122 | 0.67 | KDM4E (0.42) | KDM4EHTTKMT2AMEN1MAPT | |
| SCHEMBL1461233 | 0.64 | KMT2A (0.56) | KDM4ELMNAHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083866-A1 | QUINOLINE DERIVATIVES AS ANTI-CANCER AGENTS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2012-06-28 | — | — | WO | disclosed |