Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22129275 | 0.86 | ACE2 (0.61) | ADORA3ABCG2ABCB1ABCC1KDM4E | |
| SCHEMBL9958972 | 0.80 | ABCG2 (0.64) | ABCG2ABCB1ABCC1KDM4EACE2 | |
| Pentaacetylquercetin SCHEMBL4064499 | 0.78 | ADORA3 (0.77) | ADORA3ABCG2ABCB1ABCC1KDM4E | |
| SCHEMBL10534553 | 0.78 | ABCG2 (0.84) | ADORA3ABCG2ABCB1ABCC1KDM4E | |
| SCHEMBL9960417 | 0.77 | ABCG2 (0.57) | ABCG2ABCB1ABCC1KDM4EACE2 | |
| SCHEMBL23483932 | 0.76 | ADORA3 (0.69) | ADORA3ABCG2ABCB1ABCC1KDM4E | |
| SCHEMBL23278846 | 0.74 | ADORA3 (0.72) | ADORA3ABCG2ABCB1ABCC1KDM4E | |
| SCHEMBL10860044 | 0.73 | ADORA3 (0.57) | ADORA3ABCG2ABCB1ABCC1KDM4E | |
| SCHEMBL9958243 | 0.73 | TUBB4A (0.66) | ABCG2ABCB1ABCC1KDM4EMEN1 | |
| SCHEMBL23442020 | 0.72 | EPHX2 (0.71) | ADORA3ABCG2ABCB1ABCC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468741-A1 | Novel quercetin derivatives, their preparation, pharmaceutical compositions containing them and their use | Bel/Novamann International s.r.o. (SK) | 2012-06-27 | — | — | EP | disclosed |