SCHEMBL995905

SCHEMBL995905

CC(C)CCCC(C)NC(=O)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 3/20 0.43
ESR1 P03372 1/20 0.40
KCNH2 Q12809 1/20 0.40
ALDH1A1 P00352 2/20 0.38
POLB P06746 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
BLM P54132 1/20 0.37
TAS1R3 Q7RTX0 2/20 0.37
TAS1R1 Q7RTX1 2/20 0.37
TAS1R2 Q8TE23 2/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HRH3 Q9Y5N1 1/20 0.35
EPHX1 P07099 1/20 0.35
HTT P42858 1/20 0.35
LMNA P02545 2/20 0.35
CA2 P00918 2/20 0.33
CA3 P07451 2/20 0.33
CA5A P35218 2/20 0.33
CA5B Q9Y2D0 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL566465 0.85 MLYCD (0.41) MLYCDESR1KCNH2ALDH1A1POLB
SCHEMBL566464 0.85 MLYCD (0.41) MLYCDESR1KCNH2ALDH1A1POLB
SCHEMBL7045874 0.83 MLYCD (0.57) MLYCDESR1KCNH2TAS1R3TAS1R1
SCHEMBL7230653 0.82 ESR1 (0.41) MLYCDESR1KCNH2ALDH1A1POLB
SCHEMBL12926140 0.81 MLYCD (0.39) MLYCDESR1KCNH2ALDH1A1POLB
SCHEMBL15942204 0.81 MLYCD (0.42) MLYCDESR1KCNH2ALDH1A1POLB
SCHEMBL27905936 0.81 ALDH1A1 (0.59) MLYCDESR1KCNH2ALDH1A1POLB
SCHEMBL7230655 0.80 ALDH1A1 (0.46) MLYCDESR1KCNH2ALDH1A1POLB
SCHEMBL18287169 0.79 MLYCD (0.39) MLYCDALDH1A1BLMTAS1R3TAS1R1
SCHEMBL25134681 0.78 MLYCD (0.53) MLYCDESR1KCNH2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11161102-B2 Iminium salt organocatalysts, method of making, and methods of using UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2021-11-02 US disclosed
US-20190344253-A1 IMINIUM SALT ORGANOCATALYSTS, METHOD OF MAKING, AND METHODS OF USING UNIV VIRGINIA PATENT FOUNDATION (US) 2019-11-14 US disclosed
WO-2017223287-A1 IMINIUM SALT ORGANOCATALYSTS, METHODS OF MAKING, AND METHODS OF USING UNIVERSITY OF VIRGINIA (US) 2017-12-28 WO disclosed
US-20110015397-A1 Selective Aliphatic C-H Oxidation THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2011-01-20 US disclosed
US-7829342-B2 composition including a complex of a metal, a tetradentate ligand, at least one ancillary ligand, and a counterion is used for selective sp3 C H bond oxidation; includes a N-heterocyclic-N,N'-bis(pyridyl)-ethane-1,2-diamine group or a N,N'-bis(heterocyclic)-N,N'-bis(pyridyl)-ethane-1,2-diamine group THE BOARD OF TRUSTEES OF THE UNIVERSIY OF ILLINOIS (US) 2010-11-09 US disclosed
US-20090221083-A1 Selective Aliphatic C-H Oxidation BOARD OF TRUSTEES OF UNIVERSITY OF ILLINOIS (US) 2009-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015397-A1 Selective Aliphatic C-H Oxidation AOC3, SOD3, AP3S1 MLYCD 740/4885ESR1 1211/4885KCNH2 317/4885
US-20090221083-A1 Selective Aliphatic C-H Oxidation AOC3, SOD3, AP3S1 MLYCD 740/4885ESR1 1211/4885KCNH2 317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.