SCHEMBL9959384

SCHEMBL9959384

CCOc1cc2cccc(O)c2nc1-c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.49
KMT2A Q03164 5/20 0.45
MEN1 O00255 4/20 0.45
NPC1 O15118 4/20 0.45
RAB9A P51151 2/20 0.45
CASP3 P42574 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
ADORA3 P0DMS8 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
AGTR1 P30556 1/20 0.43
ATM Q13315 1/20 0.43
CCR6 P51684 1/20 0.43
MAPT P10636 4/20 0.42
TLR8 Q9NR97 1/20 0.41
ALOX5 P09917 1/20 0.41
SMPD3 Q9NY59 1/20 0.41
LMNA P02545 2/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2858652 0.84 KDM4E (0.49) KDM4EKMT2AMEN1NPC1RAB9A
SCHEMBL28695684 0.78 TLR8 (0.62) KDM4ENPC1RAB9AMAPTTLR8
SCHEMBL6256195 0.77 KDM4E (0.57) KDM4EKMT2AMEN1RAB9AMAPT
SCHEMBL7120189 0.76 PDE10A (0.57) KDM4EKMT2AMEN1RAB9AADORA2A
SCHEMBL10913571 0.74 KDM4E (0.54) KDM4EKMT2AMEN1ADORA3ADORA2A
SCHEMBL20564510 0.70 TLR8 (0.50) KDM4EKMT2AMEN1NPC1RAB9A
SCHEMBL1978317 0.69 L3MBTL1 (0.47) KMT2AMEN1ADORA3ADORA2AADORA1
SCHEMBL4558234 0.68 METAP2 (0.53) KDM4EKMT2AMEN1NPC1RAB9A
Oxyquinoline SCHEMBL11594833 0.68 MMP2 (0.66) KDM4EKMT2AMEN1NPC1RAB9A
SCHEMBL12014777 0.68 ATM (0.47) KDM4ECASP3ATMMAPTSMPD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2654432-A2 VOLATILE ORGANIC COMPOUNDS FROM BACTERIAL ANTAGONISTS FOR CONTROLLING MICROBIAL GROWTH Research Center Pharmaceutical Engineering GmbH (AT) 2013-10-30 EP disclosed
WO-2012085255-A2 VOLATILE ORGANIC COMPOUNDS FROM BACTERIAL ANTAGONISTS FOR CONTROLLING MICROBIAL GROWTH RESEARCH CENTER PHARMACEUTICAL ENGINEERING GMBH (AT) 2012-06-28 WO disclosed