SCHEMBL1978317

SCHEMBL1978317

CCOc1cccc(O)c1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.47
GLA P06280 1/20 0.47
ALOX5 P09917 1/20 0.46
ADORA3 P0DMS8 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA1 P30542 1/20 0.44
MAPT P10636 4/20 0.44
GAA P10253 3/20 0.44
MAPK1 P28482 1/20 0.44
ALDH1A1 P00352 4/20 0.44
PDK2 Q15119 1/20 0.43
CDK5 Q00535 1/20 0.42
CDK5R1 Q15078 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
POLB P06746 1/20 0.42
JAK2 O60674 1/20 0.41
LMNA P02545 1/20 0.41
TDP1 Q9NUW8 3/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL28083216 0.88 L3MBTL1 (0.45) L3MBTL1GLAALOX5ADORA3ADORA2A
Acrylic Acid SCHEMBL16760991 0.88 L3MBTL1 (0.45) L3MBTL1GLAALOX5ADORA3ADORA2A
SCHEMBL2173148 0.87 ALDH1A1 (0.47) L3MBTL1GLAALOX5MAPTGAA
SCHEMBL27587485 0.86 LMNA (0.47) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL28766432 0.86 ADORA3 (0.47) L3MBTL1GLAALOX5ADORA3MAPT
SCHEMBL27812775 0.86 ALOX5 (0.52) L3MBTL1GLAALOX5ADORA3ADORA2A
SCHEMBL28002540 0.85 CYP1A2 (0.49) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL29205221 0.82 CNR2 (0.50) MAPTGAAMEN1KMT2AJAK2
SCHEMBL3187650 0.82 PDK2 (0.50) L3MBTL1GLAALOX5MAPTGAA
SCHEMBL30396958 0.82 PDK2 (0.50) L3MBTL1GLAALOX5MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4326892-A1 METHOD FOR SELECTING ECOBIOLOGICAL TOPICAL COMPOSITIONS AND INGREDIENTS CAPABLE OF RESTORING OR REINFORCING THE SKIN MICROBIOTA NAOS Institute of Life Science (FR) 2024-02-28 EP claimed
WO-2022223928-A1 METHOD FOR SELECTING ECOBIOLOGICAL TOPICAL COMPOSITIONS AND INGREDIENTS CAPABLE OF RESTORING OR REINFORCING THE SKIN MICROBIOTA NAOS INSTITUTE OF LIFE SCIENCE (FR) 2022-10-27 WO claimed
US-20210030141-A1 MASK, DEVICE, AND METHOD FOR WHITENING SKIN GOO BONCHEOL (KR) 2021-02-04 US claimed
WO-2018110273-A1 A COMPOSITION INCLUDING SPARINGLY WATER-SOLUBLE ACTIVE PHENOLIC COMPOUND AND VINYLPYRROLIDONE COPOLYMER L'OREAL (FR) 2018-06-21 WO claimed
CN-121731148-A Mesoporous silica nanoparticle whitening essence loaded with whitening active ingredients 中航科学研究院(广东)有限公司 2026-03-27 CN disclosed
EP-4554549-A1 COMPOSITION COMPRISING SKIN CARE ACTIVE INGREDIENT OR CELLULOSE COMPOUND L'OREAL (FR) 2025-05-21 EP disclosed
WO-2025098792-A1 USE OF A SKIN BENEFIT AGENT IN RESTORING SKIN'S BARRIER FUNCTION UNILEVER IP HOLDINGS B.V. (NL) 2025-05-15 WO disclosed
WO-2025098825-A1 A PERSONAL CARE COMPOSITION AND A METHOD OF TREATING SKIN UNILEVER IP HOLDINGS B.V. (NL) 2025-05-15 WO disclosed
WO-2025098793-A1 USE OF A SKIN BENEFIT AGENT IN BOOSTING SKIN'S NIGHT REPAIR FUNCTION UNILEVER IP HOLDINGS B.V. (NL) 2025-05-15 WO disclosed
US-20250073154-A1 (POLY)GLYCERIN GROUP- AND POLYOXYALKYLENE GROUP-CONTAINING ORGANOPOLYSILOXANE, TREATED HYDROPHOBIC POWDER, DISPERSION, AND COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-03-06 US disclosed
EP-4516281-A1 COSMETIC COMPOSITIONS The Boots Company plc (GB) 2025-03-05 EP disclosed
US-20250064703-A1 COMPOSITION COMPRISING SOLUBILIZED POLYPHENOL OREAL (FR) 2025-02-27 US disclosed
WO-2017079905-A1 A COSMETIC COMPOSITION FOR SKIN BRIGHTENING HENKEL AG & CO. KGAA (DE) 2017-05-18 WO disclosed
US-20160000691-A1 Topical Compositions And Methods For Whitening Skin ELC MAN LLC (US) 2016-01-07 US disclosed
CN-102106642-B Cosmetic kit formulation OREAL 2014-09-17 CN disclosed
US-20110171288-A1 TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN MOHAMMADI FATEMEH 2011-07-14 US disclosed
CN-102106642-A Cosmetic kit formulation OREAL 2011-06-29 CN disclosed
US-20110142897-A1 PROCESS FOR TREATMENT OF KERATINOUS MATERIALS AND KIT FOR FORMULATION OF A COSMETIC PRODUCT L'OREAL (FR) 2011-06-16 US disclosed
EP-2254546-A2 TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN ELC Management LLC (US) 2010-12-01 EP disclosed
WO-2009105294-A2 TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN ELC MANAGEMENT LLC (US) 2009-08-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160000691-A1 Topical Compositions And Methods For Whitening Skin CUTA, COL14A1, KRT18 L3MBTL1 4866/4885GLA 9/4885ALOX5 69/4885
US-20250064703-A1 COMPOSITION COMPRISING SOLUBILIZED POLYPHENOL PROC, GANC, LGALS1 L3MBTL1 4858/4885GLA 24/4885ALOX5 828/4885
US-20250073154-A1 (POLY)GLYCERIN GROUP- AND POLYOXYALKYLENE GROUP-CONTAINING ORGANOPOLYSILOXANE, TREATED HYDROPHOBIC POWDER, DISPERSION, AND COSMETIC ALG1, PLOD3, LIPA L3MBTL1 2058/4885GLA 11/4885ALOX5 1773/4885
US-20110142897-A1 PROCESS FOR TREATMENT OF KERATINOUS MATERIALS AND KIT FOR FORMULATION OF A COSMETIC PRODUCT CUTA, KRT18, KIT L3MBTL1 4548/4885GLA 145/4885ALOX5 2768/4885
US-20110171288-A1 TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN CUTA, COL14A1, KRT18 L3MBTL1 4866/4885GLA 9/4885ALOX5 69/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.