SCHEMBL9959692

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL168939	0.86	DDR1 (0.43)	PDE2ADDR1AGPAT2PDE10ARORC
	SCHEMBL15426450	0.85	DDR1 (0.44)	PDE2ADDR1AGPAT2CNR2RORC
	SCHEMBL15426342	0.84	NLRP3 (0.45)	AGPAT2PDE10ANPC1RAB9AKDM4E
	SCHEMBL14678205	0.84	DDR1 (0.42)	PDE2ADDR1AGPAT2PDE10ACNR2
	SCHEMBL18819850	0.83	PDE2A (0.41)	PDE2ADDR1AGPAT2PDE10ACNR2
	SCHEMBL23961249	0.82	USP1 (0.43)	PDE2ADDR1CNR2NPC1RAB9A
	SCHEMBL15412012	0.82	POLB (0.46)	PDE2ADDR1KDM4EALDH1A1ACSS2
	SCHEMBL15427223	0.82	AGPAT2 (0.39)	PDE2ADDR1AGPAT2CNR2RORC
	SCHEMBL9959782	0.81	RORC (0.41)	PDE2ADDR1RORC
	SCHEMBL9959602	0.81	PDE2A (0.40)	PDE2ADDR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.