Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9960728 | 1.00 | PKM (0.33) | PKMALDH1A1POLBPPARGPPARA | |
| SCHEMBL9960826 | 0.84 | LTB4R (0.36) | ALDH1A1POLBCYP1A2TSHR | |
| SCHEMBL9960707 | 0.81 | ALDH1A1 (0.35) | ALDH1A1POLBCYP1A2TSHRHBB | |
| SCHEMBL9960749 | 0.74 | KCNN4 (0.36) | ALDH1A1CYP1A2TSHREDNRBEDNRA | |
| SCHEMBL9960644 | 0.72 | KEAP1 (0.39) | PKM | |
| SCHEMBL1492728 | 0.68 | CYP2C19 (0.50) | ALDH1A1RIPK1CYP1A2TSHRMAPT | |
| SCHEMBL6908484 | 0.67 | PPARG (0.42) | ALDH1A1PPARGPPARAMAPT | |
| SCHEMBL28727593 | 0.67 | CYP2C19 (0.48) | ALDH1A1RIPK1CYP1A2TSHRMAPT | |
| SCHEMBL28938744 | 0.67 | CYP2C19 (0.48) | ALDH1A1RIPK1CYP1A2TSHRMAPT | |
| Bicarbonate SCHEMBL29088377 | 0.66 | POLB (0.35) | ALDH1A1POLBCYP1A2TSHRHBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655311-A1 | INGENOL-3-ACYLATES I | LEO LABORATORIES LIMITED (IE) | 2013-10-30 | — | — | EP | claimed |
| WO-2012085189-A1 | INGENOL-3-ACYLATES I | LEO PHARMA A/S (DK) | 2012-06-28 | — | — | WO | claimed |