Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799312 | 0.81 | KCNH2 (0.46) | KCNH2CNR1MAPK1SLC6A3SMN1; SMN2 | |
| SCHEMBL3959636 | 0.81 | KCNH2 (0.46) | KCNH2CNR1MAPK1SLC6A3SMN1; SMN2 | |
| SCHEMBL6330057 | 0.81 | KCNH2 (0.46) | KCNH2SLC6A3IDO1ADRA1ASIGMAR1 | |
| SCHEMBL29206281 | 0.81 | KCNH2 (0.42) | KCNH2CNR1ACP3GRIK1MAPK1 | |
| SCHEMBL9305769 | 0.78 | KCNH2 (0.46) | KCNH2SIGMAR1MAPT | |
| SCHEMBL9659732 | 0.78 | KCNH2 (0.46) | KCNH2SIGMAR1MAPT | |
| SCHEMBL10717425 | 0.78 | KCNH2 (0.46) | KCNH2SIGMAR1MAPT | |
| SCHEMBL9617062 | 0.78 | SLC7A5 (0.42) | SMN1; SMN2SIGMAR1RAB9A | |
| SCHEMBL704017 | 0.77 | KCNH2 (0.42) | KCNH2CNR1MAPK1SLC6A3SMN1; SMN2 | |
| SCHEMBL708047 | 0.77 | KCNH2 (0.42) | KCNH2CNR1MAPK1SLC6A3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9050176-B2 | At least partially resorbable reticulated elastomeric matrix elements and methods of making same | BIOMERIX CORPORATION (US) | 2015-06-09 | — | — | US | disclosed |
| US-8846845-B2 | Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices | BEZWADA BIOMEDICAL, LLC (US) | 2014-09-30 | — | — | US | disclosed |
| US-20120239161-A1 | AT LEAST PARTIALLY RESORBABLE RETICULATED ELASTOMERIC MATRIX ELEMENTS AND METHODS OF MAKING SAME | BIOMERIX CORPORATION (US) | 2012-09-20 | — | — | US | disclosed |
| US-20120158127-A1 | BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES | BEZWADA BIOMEDICAL, LLC (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120158127-A1 | BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES | HAO2, AOC2, AOC1 | KCNH2 1067/4885CNR1 1600/4885ACP3 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.