Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17557724 | 0.98 | HRH3 (0.51) | HRH3ITGB3ITGA2BLTA4HPRSS1 | |
| SCHEMBL13073181 | 0.94 | ITGB3 (0.55) | HRH3ITGB3ITGA2BLTA4HPRSS1 | |
| SCHEMBL26961928 | 0.92 | ITGB3 (0.58) | HRH3ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL29796753 | 0.90 | ITGB3 (0.56) | HRH3ITGB3ITGA2BPRSS1 | |
| SCHEMBL10488336 | 0.89 | LTA4H (0.60) | HRH3LTA4HTAAR1KEAP1NFE2L2 | |
| SCHEMBL8545935 | 0.87 | HRH3 (0.59) | HRH3LTA4HPRSS1 | |
| SCHEMBL16902877 | 0.87 | HRH3 (0.59) | HRH3LTA4HPRSS1 | |
| Trifluoroacetic Acid SCHEMBL9936935 | 0.85 | CA12 (0.59) | ITGB3ITGA2B | |
| SCHEMBL8369936 | 0.85 | HRH3 (0.58) | HRH3LTA4HPRSS1 | |
| SCHEMBL16902874 | 0.85 | HRH3 (0.58) | HRH3LTA4HPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140010762-A1 | IMAGING AGENTS | CHROMA THERAPEUTICS LTD (GB) | 2014-01-09 | — | — | US | disclosed |
| US-20140010762-A1 | IMAGING AGENTS | CHROMA THERAPEUTICS LTD (GB) | 2014-01-09 | — | — | US | disclosed |
| WO-2012080705-A1 | IMAGING AGENTS | CHROMA THERAPEUTICS LTD (GB) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140010762-A1 | IMAGING AGENTS | CES1, CES2, NCEH1 | HRH3 1152/4885ITGB3 2102/4885ITGA2B 3447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.