Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.43 |
| ▸ | UBE2M | P61081 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965381 | 0.83 | POLB (0.53) | RXFP1MEN1KMT2ATSHRPOLB | |
| SCHEMBL1817247 | 0.79 | POLB (0.61) | RXFP1MEN1KMT2APOLBSIRT2 | |
| SCHEMBL640944 | 0.77 | GAA (0.62) | F10RXFP1MEN1KMT2ATSHR | |
| SCHEMBL24529989 | 0.76 | F10 (0.58) | F10RXFP1MEN1KMT2ATSHR | |
| SCHEMBL4035356 | 0.75 | ALDH1A1 (0.64) | F10 | |
| Hydrochloric Acid SCHEMBL23245936 | 0.75 | F10 (0.57) | F10RXFP1SIRT2 | |
| SCHEMBL16085543 | 0.75 | F10 (0.51) | F10MEN1KMT2APOLBGAA | |
| SCHEMBL7363345 | 0.74 | SIRT2 (0.50) | RXFP1MEN1KMT2ATSHRPOLB | |
| SCHEMBL5549681 | 0.72 | CFTR (0.46) | RXFP1MEN1KMT2APOLBKLKB1 | |
| SCHEMBL13588433 | 0.72 | SMN1; SMN2 (0.59) | RXFP1MEN1KMT2ATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960347-B1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 (17BETA-HSD3) INHIBITORS | STERIX LTD (GB) | 2012-06-20 | — | — | EP | disclosed |