Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1593840 | 0.85 | ALDH1A1 (0.54) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL14412293 | 0.84 | CHRNB2 (0.43) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL1594589 | 0.80 | MEN1 (0.57) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL1594477 | 0.76 | ALDH1A1 (0.57) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL14960293 | 0.76 | ALDH1A1 (0.46) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL1593887 | 0.76 | ALDH1A1 (0.56) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL14412294 | 0.74 | HDAC3 (0.45) | ALDH1A1MAPT | |
| SCHEMBL11916012 | 0.73 | KMT2A (0.59) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL4928264 | 0.72 | MMP12 (0.68) | KMT2AMEN1L3MBTL1HPGDGAA | |
| Hydrochloric Acid SCHEMBL21625705 | 0.72 | NPC1 (0.56) | KMT2AKDM4EHSD17B10GAAMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2465850-A1 | THERAPEUTIC COMPOUNDS | Helicon Therapeutics, Inc. (US) | 2012-06-20 | — | — | EP | disclosed |