Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 20/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966523 | 0.90 | IDO1 (0.36) | ALOX5AP | |
| SCHEMBL9966308 | 0.88 | ALOX5AP (0.33) | ALOX5AP | |
| SCHEMBL9966522 | 0.78 | ALOX5AP (0.38) | ALOX5AP | |
| SCHEMBL9966449 | 0.77 | MAP4K4 (0.33) | — | |
| SCHEMBL9966514 | 0.77 | MAP4K4 (0.40) | — | |
| SCHEMBL9966365 | 0.77 | USP2 (0.33) | — | |
| SCHEMBL14244230 | 0.75 | ALOX5AP (0.44) | ALOX5AP | |
| SCHEMBL9966380 | 0.75 | PIK3CA (0.33) | — | |
| SCHEMBL9966413 | 0.74 | RIPK1 (0.37) | ALOX5AP | |
| SCHEMBL9966486 | 0.73 | MAP4K4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082817-A1 | BIARYLAMIDE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |