Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 10/20 | 0.56 |
| ▸ | CCR2 | P41597 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9931317 | 0.89 | CCR2 (0.66) | PKMCCR2MEN1KMT2A | |
| SCHEMBL28614056 | 0.82 | HSPD1 (0.58) | PKMMEN1KMT2A | |
| SCHEMBL17340517 | 0.75 | PKM (0.52) | PKMCCR2MEN1KMT2A | |
| SCHEMBL9930711 | 0.74 | CCR2 (0.69) | PKMCCR2 | |
| SCHEMBL9967988 | 0.73 | CCR2 (0.68) | PKMCCR2 | |
| SCHEMBL9968200 | 0.73 | CCR2 (0.62) | PKMCCR2MEN1KMT2A | |
| SCHEMBL9930914 | 0.71 | CCR2 (0.77) | PKMCCR2MEN1KMT2A | |
| SCHEMBL9968068 | 0.71 | CCR2 (0.64) | PKMCCR2MEN1KMT2A | |
| SCHEMBL9968002 | 0.70 | CCR2 (0.54) | CCR2MEN1KMT2A | |
| SCHEMBL28607575 | 0.69 | PKM (0.72) | PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082633-A1 | NOVEL 1,2- BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2012-06-21 | — | — | WO | disclosed |