SCHEMBL9968847

SCHEMBL9968847

CC(C)OC(=O)CN1C(=O)CC(Cc2ccc(O)cc2O)C1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
TSHR P16473 1/20 0.39
ALDH1A1 P00352 5/20 0.38
HSD17B10 Q99714 1/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA14 Q9ULX7 2/20 0.38
AGTR1 P30556 1/20 0.37
PPARG P37231 1/20 0.35
MIF P14174 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390952 1.00 L3MBTL1 (0.41) L3MBTL1TSHRALDH1A1HSD17B10CA12
SCHEMBL9937992 0.88 MAPT (0.43) L3MBTL1TSHRALDH1A1HSD17B10CA12
SCHEMBL9968844 0.86 PPARG (0.45) L3MBTL1TSHRCA12CA1CA2
SCHEMBL29392707 0.86 PPARG (0.45) L3MBTL1TSHRCA12CA1CA2
SCHEMBL9938468 0.83 TSHR (0.56) L3MBTL1TSHRALDH1A1MEN1KMT2A
SCHEMBL15328838 0.82 TSHR (0.43) L3MBTL1TSHRALDH1A1MEN1KMT2A
SCHEMBL9937195 0.82 ALDH1A1 (0.39) L3MBTL1TSHRALDH1A1LMNA
SCHEMBL18675888 0.80 CA12 (0.38) CA12CA1CA2CA7CA9
SCHEMBL9937177 0.80 L3MBTL1 (0.40) L3MBTL1TSHRALDH1A1HSD17B10MEN1
SCHEMBL9968851 0.80 ALDH1A1 (0.41) L3MBTL1TSHRALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11154473-B2 Composition comprising resorcinol or derivative thereof L'OREAL (FR) 2021-10-26 US disclosed
US-20170087064-A1 COMPOSITION IN THE FORM OF NANO OR MICRO EMULSION OR WITH LAMELLAR STRUCTURE L'OREAL (FR) 2017-03-30 US disclosed
US-20170087064-A1 COMPOSITION IN THE FORM OF NANO OR MICRO EMULSION OR WITH LAMELLAR STRUCTURE L'OREAL (FR) 2017-03-30 US disclosed
WO-2015198922-A1 COMPOSITION IN THE FORM OF NANO OR MICRO EMULSION OR WITH LAMELLAR STRUCTURE L'OREAL (FR) 2015-12-30 WO disclosed
EP-2651886-B1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES ORÉAL L (FR) 2015-03-04 EP disclosed
US-8937187-B2 Method for depigmenting keratin materials using resorcinol derivatives L'OREAL (FR) 2015-01-20 US disclosed
US-8937187-B2 Method for depigmenting keratin materials using resorcinol derivatives L'OREAL (FR) 2015-01-20 US disclosed
US-20130281507-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'OREAL (FR) 2013-10-24 US disclosed
US-20130281507-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'OREAL (FR) 2013-10-24 US disclosed
WO-2012079938-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'OREAL (FR) 2012-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11154473-B2 Composition comprising resorcinol or derivative thereof NQO1, LRAT, RBP4 L3MBTL1 3046/4885TSHR 3913/4885ALDH1A1 160/4885
US-20130281507-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES KRT18, KLHL20, IK L3MBTL1 4589/4885TSHR 4359/4885ALDH1A1 222/4885
US-20170087064-A1 COMPOSITION IN THE FORM OF NANO OR MICRO EMULSION OR WITH LAMELLAR STRUCTURE LRAT, LIPA, DAGLA L3MBTL1 3662/4885TSHR 3718/4885ALDH1A1 1908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.