SCHEMBL9938468

SCHEMBL9938468

O=C(O)CN1C(=O)CC(Cc2ccc(O)cc2O)C1=O

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
ALDH1A1 P00352 3/20 0.36
TYR P14679 1/20 0.36
TACR1 P25103 1/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ALOX5 P09917 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15328838 0.89 TSHR (0.43) TSHRL3MBTL1ALDH1A1TYRTACR1
SCHEMBL9968851 0.87 ALDH1A1 (0.41) TSHRL3MBTL1ALDH1A1TYRTACR1
SCHEMBL15341257 0.87 TYR (0.40) TSHRL3MBTL1ALDH1A1TYRTACR1
SCHEMBL9937665 0.85 TSHR (0.41) TSHRL3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL9937177 0.84 L3MBTL1 (0.40) TSHRL3MBTL1ALDH1A1TYRTACR1
SCHEMBL9969790 0.84 ALDH1A1 (0.42) TSHRL3MBTL1ALDH1A1TYRTACR1
SCHEMBL29392707 0.83 PPARG (0.45) TSHRL3MBTL1MEN1USP2KMT2A
SCHEMBL9968844 0.83 PPARG (0.45) TSHRL3MBTL1MEN1USP2KMT2A
SCHEMBL9937438 0.83 ALDH1A1 (0.39) TSHRL3MBTL1ALDH1A1TYRTACR1
SCHEMBL9938330 0.83 MAPK1 (0.55) TSHRL3MBTL1ALDH1A1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2651886-B1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES ORÉAL L (FR) 2015-03-04 EP claimed
US-8937187-B2 Method for depigmenting keratin materials using resorcinol derivatives L'OREAL (FR) 2015-01-20 US claimed
US-20130281507-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'OREAL (FR) 2013-10-24 US claimed
EP-2651886-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'Oréal (FR) 2013-10-23 EP claimed
WO-2012079938-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'OREAL (FR) 2012-06-21 WO claimed
EP-3393603-B1 TOPICAL DELIVERY SYSTEM FOR ACTIVE INGREDIENTS OREAL (FR) 2023-01-18 EP disclosed
US-11260000-B2 Composition in the form of nano or micro emulsion or with lamellar structure L'OREAL (FR) 2022-03-01 US disclosed
US-11154473-B2 Composition comprising resorcinol or derivative thereof L'OREAL (FR) 2021-10-26 US disclosed
US-20190336421-A1 COMPOSITION COMPRISING RESORCINOL OR DERIVATIVE THEREOF L'OREAL (FR) 2019-11-07 US disclosed
US-20180360705-A1 TOPICAL DELIVERY SYSTEM FOR ACTIVE INREDIENTS L'OREAL (FR) 2018-12-20 US disclosed
US-20170087064-A1 COMPOSITION IN THE FORM OF NANO OR MICRO EMULSION OR WITH LAMELLAR STRUCTURE L'OREAL (FR) 2017-03-30 US disclosed
EP-2651886-B1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES ORÉAL L (FR) 2015-03-04 EP disclosed
EP-2651886-B1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES ORÉAL L (FR) 2015-03-04 EP disclosed
US-8937187-B2 Method for depigmenting keratin materials using resorcinol derivatives L'OREAL (FR) 2015-01-20 US disclosed
US-8937187-B2 Method for depigmenting keratin materials using resorcinol derivatives L'OREAL (FR) 2015-01-20 US disclosed
US-8937187-B2 Method for depigmenting keratin materials using resorcinol derivatives L'OREAL (FR) 2015-01-20 US disclosed
US-20130281507-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'OREAL (FR) 2013-10-24 US disclosed
US-20130281507-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'OREAL (FR) 2013-10-24 US disclosed
US-20130281507-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'OREAL (FR) 2013-10-24 US disclosed
WO-2012079938-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES L'OREAL (FR) 2012-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180360705-A1 TOPICAL DELIVERY SYSTEM FOR ACTIVE INREDIENTS KRT18, CUTA, DSG1 TSHR 3065/4885L3MBTL1 4421/4885ALDH1A1 1819/4885
US-11154473-B2 Composition comprising resorcinol or derivative thereof NQO1, LRAT, RBP4 TSHR 3913/4885L3MBTL1 3046/4885ALDH1A1 160/4885
US-20190336421-A1 COMPOSITION COMPRISING RESORCINOL OR DERIVATIVE THEREOF NQO1, LRAT, RBP4 TSHR 3913/4885L3MBTL1 3046/4885ALDH1A1 160/4885
US-20130281507-A1 METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES KRT18, KLHL20, IK TSHR 4359/4885L3MBTL1 4589/4885ALDH1A1 222/4885
US-20170087064-A1 COMPOSITION IN THE FORM OF NANO OR MICRO EMULSION OR WITH LAMELLAR STRUCTURE LRAT, LIPA, DAGLA TSHR 3718/4885L3MBTL1 3662/4885ALDH1A1 1908/4885
US-11260000-B2 Composition in the form of nano or micro emulsion or with lamellar structure LRAT, LIPA, DAGLA TSHR 3718/4885L3MBTL1 3662/4885ALDH1A1 1908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.