Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | USP2 | O75604 | 4/20 | 0.67 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.67 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | ATM | Q13315 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 4/20 | 0.63 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TYMS | P04818 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12856931 | 0.88 | MEN1 (0.53) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL9968959 | 0.88 | MEN1 (0.53) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL12869500 | 0.86 | KMT2A (0.73) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL9290359 | 0.86 | PKM (0.51) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL12561181 | 0.86 | PKM (0.58) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL12111266 | 0.85 | MEN1 (0.50) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL12111263 | 0.85 | MEN1 (0.50) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL20735127 | 0.85 | KMT2A (0.71) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL17231437 | 0.84 | MAPT (0.65) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL20735125 | 0.81 | KMT2A (0.67) | KMT2AMEN1USP2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170084839-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | US | disclosed |
| US-9315671-B2 | Bay-annulated indigo (BAI) as an excellent electron accepting building block for high performance organic semiconductors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-04-19 | — | — | US | disclosed |
| US-20140128388-A1 | TARGETING AN HIV-1 NEF-HOST CELL KINASE COMPLEX | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2014-05-08 | — | — | US | disclosed |
| US-8541415-B2 | Targeting an HIV-1 nef-host cell kinase complex | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2013-09-24 | — | — | US | disclosed |
| US-8293695-B2 | Shading composition | BASF SE (DE) | 2012-10-23 | — | — | US | disclosed |
| US-8202994-B2 | Pentarylene- and hexarylenetetracarboximides and preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 2012-06-19 | — | — | US | disclosed |
| US-8071761-B2 | Substrates for beta-lactamase and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-06 | — | — | US | disclosed |
| EP-1861886-B1 | ORGANIC PHOTOACTIVE COMPONENT | HELIATEK GMBH (DE) | 2011-07-06 | — | — | EP | disclosed |
| US-20100299849-A1 | SHADING PROCESS | HOEHENER ALFRED | 2010-12-02 | — | — | US | disclosed |
| US-7820780-B2 | Polymers of napthalene tetracarboxylic diimide dimers | XEROX CORPORATION (US) | 2010-10-26 | — | — | US | disclosed |
| US-20100059716-A1 | PENTARYLENE-AND HEXARYLENETETRACARBOXIMIDES AND PREPARATION THEREOF | BASF SE (DE) | 2010-03-11 | — | — | US | disclosed |
| US-20090234092-A1 | POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS | XEROX CORPORATION (US) | 2009-09-17 | — | — | US | disclosed |
| US-20090217980-A1 | Organic Photoactive Device | HELIATEK GMBH (DE) | 2009-09-03 | — | — | US | disclosed |
| US-7544450-B2 | Polymers of napthalene tetracarboxylic diimide dimers | XEROX CORPORATION (US) | 2009-06-09 | — | — | US | disclosed |
| US-20090105108-A1 | Shading Process | CIBA CORPORATION | 2009-04-23 | — | — | US | disclosed |
| US-7449268-B2 | Polycarbonates, polyesters and polyimides from the dimers exhibit properties of both binders and an electron-transporting materials; electrographic and photoconductor elements | XEROX CORPORATION (US) | 2008-11-11 | — | — | US | disclosed |
| US-20080171275-A1 | POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS | XEROX CORPORATION (US) | 2008-07-17 | — | — | US | disclosed |
| US-20070184513-A1 | Substrates for beta-lactamase and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-09 | — | — | US | disclosed |
| US-20070020715-A1 | Novel fluorogenic substrates for beta-lactamase gene expression | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-01-25 | — | — | US | disclosed |
| US-7157575-B2 | Substrates for β-lactamase and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100059716-A1 | PENTARYLENE-AND HEXARYLENETETRACARBOXIMIDES AND PREPARATION THEREOF | CYP2C9, PNPO, CYP3A43 | KMT2A 3106/4885MEN1 1512/4885USP2 340/4885 |
| US-20170084839-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | PPOX, OSTC, OCIAD1 | KMT2A 1869/4885MEN1 3348/4885USP2 4770/4885 |
| US-20070020715-A1 | Novel fluorogenic substrates for beta-lactamase gene expression | CMBL, HRH3, TDO2 | KMT2A 803/4885MEN1 4239/4885USP2 1296/4885 |
| US-20140128388-A1 | TARGETING AN HIV-1 NEF-HOST CELL KINASE COMPLEX | HCK, DCK, NCK1 | KMT2A 2043/4885MEN1 4852/4885USP2 2709/4885 |
| US-20070184513-A1 | Substrates for beta-lactamase and uses thereof | CMBL, DBH, NCEH1 | KMT2A 1021/4885MEN1 3743/4885USP2 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.